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  • Oprah Winfrey, one of the 2010 Kennedy Center honorees, arrives...

    Oprah Winfrey, one of the 2010 Kennedy Center honorees, arrives with Stedman Graham for the Artist's Dinner at the United States Department of State in Washington, D.C., U.S., on Saturday, Dec. 4, 2010. The Kennedy Center Honors gala is scheduled to be televised on CBS Dec. 28. Photographer: Ron Sachs/Pool via Bloomberg *** Local Caption *** Oprah Winfrey; Stedman Graham

  • In this photo taken April 23, 2009 and provided by...

    In this photo taken April 23, 2009 and provided by Harpo Productions, Inc., talk-show host Oprah Winfrey raises a champagne toast to Dr. Mehmet Oz, her in-house medical and health expert, during taping of "The Oprah Winfrey Show" in Chicago. The show will air nationally on Tuesday, May 12, 2009. Oz is leaving his spot as a regular on the show to launch his own syndicated program this fall. (AP Photo/Harpo Productions, Inc., George Burns) **MANDATORY CREDIT: Harpo Productions, George Burns. NO SALES**

  • Oprah Winfrey speaks with actor Tom Cruise during a press...

    Oprah Winfrey speaks with actor Tom Cruise during a press conference, Saturday, Dec. 11, 2004, in Oslo, Norway. Cruise and Winfrey will be the hosts of the concert on Saturday for Nobel Peace Prize laureate Wangari Maathai.

  • In this photo taken April 30, 2011, talk-show host Oprah...

    In this photo taken April 30, 2011, talk-show host Oprah Winfrey, right, interviews author James Frey in New York during taping for "The Oprah Winfrey Show." The interview will stretch over two episodes on May 16-17. Winfrey chose Frey's substance abuse story "A Million Little Pieces," for her book club in September 2005, making it a million-seller. Frey subsequently acknowledged on Winfrey's show in January 2006 that he had lied in the book. Winfrey told him she felt duped and that he had betrayed millions of readers.

  • Singer Celine Dion and Oprah Winfrey hug during a break...

    Singer Celine Dion and Oprah Winfrey hug during a break in the taping of 'The Oprah Winfrey Show' at Walt Disney World in Orlando, Fla., on Saturday, April 27, 1996. Dion performs several of her hit songs on the show, which airs on Wednesday, May 15, 1996.

  • 1. Weight loss, 1988, (that indelible photo of her pulling...

    1. Weight loss, 1988, (that indelible photo of her pulling 68 pounds worth of fat in a little red wagon).

  • 3. Car giveaway, 2004. Great moments in cross-promotion. The beneficent...

    3. Car giveaway, 2004. Great moments in cross-promotion. The beneficent host bestows $7 million worth of vehicles. "Everybody gets a car!"

  • Democratic presidential hopeful, Sen. Barack Obama, D-Ill.. waves to supporters...

    Democratic presidential hopeful, Sen. Barack Obama, D-Ill.. waves to supporters as he stands with Oprah Winfrey during a rally, Saturday, Dec. 8, 2007, in Des Moines, Iowa.

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Joanne Ostrow of The Denver Post.
PUBLISHED: | UPDATED:

Oprah Winfrey will leave behind a few tears and many indelible memories when she concludes her syndicated show Wednesday (locally 4-5 p.m. on KCNC-Channel 4) after 25 years of steamroller ratings, 47 Emmy Awards and a lifetime of culture-changing talk. Among the high points . . .

1. Weight loss, 1988, (that indelible photo of her pulling 68 pounds worth of fat in a little red wagon).

2. Empathy central. For abuse, humiliation, hurt of every variety, she’s the nation’s hand-holder. According to O, Oprah’s monthly magazine, she’s cried on camera 79 times.

3. Car giveaway, 2004. Great moments in cross-promotion. The beneficent host bestows $7 million worth of vehicles. “Everybody gets a car!”

4. Her feud with David Letterman, 2005, parlayed into a seriously cute Super Bowl commercial featuring them snuggling on the couch.

5. Oprah’s Book Club, a victory for literacy. The artistic merits of her picks are debatable, but the country is better off with more people reading.

6.Hail to the Schmoozer-in-Chief: Oprah endorsed Barack Obama in 2008. When he and Michelle Obama visited this month, he was the first sitting president to appear on her show; five U.S. presidents have had an audience with Herself at one time or another.

7. Heart surgeon Mehmet Oz joined Oprah’s show in 2004; launched his own show, “Dr. Oz,” in 2009.

8. With a splash of spirituality. Encouraging viewers to “live your best life,” she draws on Eckhart Tolle, Marianne Williamson and other seers.

9. Starmaking machinery: Dr. Phil. With the nurturing and shaping of this emerging star, her ability as TV talent scout is unparalleled.

10. Rachel Ray, Nate Berkus, further adventures in starmaking. Plus Art Smith, her personal chef.

11. That little jaunt to Australia, with audience.

12. Her surprise 50th birthday party, thrown by Gayle King and John Travolta.

13. Veggie burgers all around. Her beef with the beef industry over mad cow disease; the production relocated to Amarillo, Texas, during the 1998 trial. (She won the libel lawsuit against cattle interests who said her remarks depressed beef prices.)

14. Most frequent guest, not counting Gayle, was Celine Dion, booked 27 times.

15. Her ginormous checkbook opened to the Denver School of Science and Technology, and she dropped a cool $1 million on it in 2010.

16. Stedman Graham, the engagement, the couple that is or almost was.

17. Oh, and the Gayle King rumors that won’t die.

18. James Frey brouhaha: After she championed his book “A Million Little Pieces,” it was revealed to be largely fiction. Talking redemption, she got more shows out of it.

19. Tom Cruise couch freakout. Who cares what got him jumping? It’s the 2005 visual we’ll remember. Associated Press file

20. Imagine whirled peas. Nobel Peace Prize winners have appeared on the show, but fans mounted a campaign to put Oprah herself in nomination for the prize in 2005.

21. Weight gain, with flashbacks to that damn fat in the red wagon.

22. Philanthropy, Oprah style: “The Big Give,” short-lived ABC reality-game show from Harpo Productions, hosted by Berkus, offered those who gave away the most money a chance to win $1 million.

23. The 2010 launch of OWN, after months of hype, was a fizzle. Expect to see more of Winfrey on OWN, in reruns and otherwise, in the future. Her signature show, “Oprah’s Next Chapter,” has been delayed until January 2012.

24. Filming for posterity: “Oprah Behind the Scenes,” a “documentary” of the talk-show’s last season, is the most popular series on OWN.

25. The May 25 “Farewell Spectacular” with Maria Shriver, Madonna, Michael Jordan, Will and Jada Smith, and other pals. Commercial time is selling for $1 million per spot in the finale. The truth is, she’s still keeping us guessing.

Joanne Ostrow: 303-954-1830 or jostrow@denverpost.com

After Oprah

After Wednesday’s finale, KCNC will carry “Oprah” reruns before debuting a 4 p.m. newscast in June. (The start date for “CBS4 at 4” isn’t fixed, pending contractual obligations with Harpo. Assume it will happen after the May ratings sweeps.) Co-anchors Karen Leigh and Michelle Griego and weather guy Ed Greene are in rehearsals for a “harder-edged” news program. “There won’t be a crockpot on the set,” says CBS4 boss Walt de Haven.

View photos from the “Oprah Farewell Spectacular”.

View photos of Oprah through the years.