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2015, Iranian journal of pharmaceutical research : IJPR
Rosa damascena, Tripleurospermum disciforme and Securigera securidaca were used as disinfectant agents and for treatment of some disease in folk medicine of Iran. The antimicrobial effects of different fractions of seeds extract of S. securidaca, petals extract of R. damascena and aerial parts extract of T. disciforme were examined against some gram positive, gram negative and fungi by cup plate diffusion method. The petroleum ether and chloroform fractions of S. securidaca showed antibacterial activities against Staphylococcus aureus and Pseudomonas aeruginosa, while its methanol fraction had no antibacterial effects. R. damascena petals extract demonstrated antibacterial activities against Bacillus cereus, Staphylococcus epidermidis, S. aureus and Pseudomonas aeruginosa. T. disciforme aerial parts extract exhibited antimicrobial effects only against S. aureus and S. epidermidis. None of the fractions had any antifungal activities. Therefore, present study confirmed utility of thes...
2022 •
Plants have a wealth of medicinal chemicals with vast potential in the pharmaceutical sector. The purpose of this research was to determine which phytochemicals were present in the seven medicinal plants chosen for this study, as well as to determine whether or not these plants have any antibacterial or antioxidant properties. Methods. The total phenolic and flavonoid contents, as well as the results of a standard phytochemical screen, were calculated. The antioxidant activity of plant extracts was determined using 2, 2-diphenyl-1-picrylhydrazyl (DPPH), hydroxyl (OH), and nitric oxide (NO) radical scavenging assays. The broth microdilution technique was used to test the plant extracts for antibacterial activity. Phenols, flavonoids, and steroids were found in every plant extract analyzed by phytochemical methods. The extract of Psychotria peduncularis showed the highest total phenolic and flavonoid contents (5.57 •} 0.22 mg GAE/g and 1.38 •} 0.06 mg QE/g, respectively). The IC50 values for DPPH radical scavenging and NO radical scavenging ranged from 0.55 to 49.43 g/mL and 0.65 to 13.7 g/mL, respectively, indicating that all plant extracts exhibited extremely significant antioxidant activity. With MIC values ranging from 16 to 1024 g/mL, extracts of both Tristemma Mauritian rum and P. peduncularis showed potent antibacterial activity. Extracts of T. Mauritian rum were bactericidal against all species examined. There was substantial antifungal activity (MIC 64 g/mL) observed between Candida albicans and extracts of Alsophila Marianna and P. peduncular. Our research suggests that the screened extracts of medicinal plants might be employed as resources for the creation of novel medications, namely as antioxidant and antibacterial agents.
2014 •
The ethanolic extracts of the eight medicinal plants were tested to determine antibacterial activities against fourteen gram positive and twenty two gram negative bacteria. Five out of eight extracts revealed prominent antibacterial activity. Ampicillin was used as a standard for anti-bacterial activity. The significant zone of inhibition was exhibited by Digitalis purpurae (23±2) against Corynebacterium hofmanii . Sambucus nigra and Urtica urens exhibited minimum inhibitory concentration (12 mg/ml) against Staphylococcus epidermidis and Streptococcus fecalis . Saprophytes, dermatophytes and yeasts were used to screen antifungal activities of these selected medicinal plants. Griseofulvin was used as a standard anti-fungal drug. Four out of eight of the tested plant extracts had significant antifungal activity. Urtica uren produced the most significant zone of inhibition (32±1) against Rhizopus specie. Whereas the lowest minimum inhibitory concentration was exhibited by Urtica urens ...
2019 •
This study sought to investigate the antimicrobial activity of sixBackground: plants used in traditional medicine in Africa. The antimicrobial activity of the six medicinal plant extracts (aqueousMethods: and ethanol) were evaluated against (ATCC 21784), Proteus mirabilis (ATCC27856) were using thePseudomonas aeruginosa Aspergillus fumigatus agar-well diffusion protocol. The activities of these extracts were compared with the positive controls chloramphenicol and griseofulvin. Similarly, the phytochemicals from the extracts were qualitatively assayed and their percentage yield calculated by standard methods. The bacterial organisms used, and , wereResults: P. mirabilis P. aeruginosa slightly-to-highly susceptible to aqueous and ethanolic extracts from the various test plants, while was insensitive to the treatments. The ethanolic A. fumigatus extracts of the sampled plants showed superior inhibitory performance on the target bacteria to the aqueous extracts. Aqueous and eth...
AkiNik
In vitro antimicrobial activity and preliminary phytochemical screening of some plant extracts2020 •
Antimicrobial activity of five solvent extracts of local plants was evaluated in vitro, with four strains of bacteria viz., Salmonella typhi, Escherichia coli, Shigella flexneri (gram-ve), Staphylococcus aureus (gram +ve) and four strains of fungi viz., Alternaria alternata, Penicillium notatum, Aspergillus niger, Penicillium digitatum microorganism. The in vitro antibacterial and antifungal activities were tested by agar disc diffusion method. The most active antibacterial plants were Vitex negundo, Tagetes erecta and antifungal plants were Xanthium strumarium, Vitex negundo and Tagetes erecta, respectively. The significant antimicrobial activities of potent extracts were compared with the standard antimicrobiotics, Ciprofloxacin and Fluconazole for bacteria as well as fungi respectively at 1 mg/ml concentration. Preliminary phytochemical analysis of V. negundo leaf, X. strumarium, M. pruriens, C. bonduc seed and T. erecta flower extracts generally revealed the presence of Alkaloids, Steroids, Terpenoids, Phenols, Saponins, Anthraquinones, Amino acids, Carotenoids, Flavonoids and Tannins at various concentrations. The results obtained in this study suggest that X. strumarium, V. negundo, T. erecta can be used in treating diseases caused by these test organisms.
The antibacterial activity of various solvent extracts of medicinal plants was evaluated against the human pathogenic bacteria Escherichia coli, Klebsiella pneumonia, Bacillus subtilis Bacillus cereus, Salmonella typhi, Enterobacter aerogenes and Staphylococcus aureus by agar cup diffusion method. Methanol extracts of Clerodendrum inerme L., Terminalia chebula Retz., Curcuma amada Roxb., Anacardium occidentale L., Duranta repens L., Eucalyptus camaldulenis Dehnh and Euphorbia cotinifolia L. showed significant activity. The petroleum ether and chloroform extracts of Terminalia chebula, Curcuma amada and Piper betel also showed promising results. The antibacterial activity of promising plant extracts when compared with standard drugs streptomycin and gentamycin recorded siginificant inhibition. Phytochemical analysis of the different extracts of the screened plants indicated the presence of flavanoids, terpinoids, tannins steriodas, alkaloids and glysocides. The positive results of screening of medicinal plants for antibacterial activity forms primary platform for further phytochemical and pharmacological studies.
International Journal for Research in Applied Sciences and Biotechnology
Antibacterial Effect of Some Medicinal Plants against Staphylococcus aureus and Pseudomonas aeruginosa2018 •
International Journal for Research in Applied Sciences and Biotechnology Journal, Meison Abdulbary
Multidrug resistant microorganisms are globally becoming a major confrontment because of illogical use of antibiotics and this played a good role in investigation about the antibacterial compounds in plants. Thus, the present study investigate for the antibacterial effect of alcoholic extracts of Curcuma longa L. rhizomes , CommiphoramyrrhaL. gums and Ginkgo biloba L. leaves products against Staphylococcus aureus and Pseudomonas aeruginosa. The plants samples extracted by soxhlet with methanol and fractionation with and four solution (chloroform, hexane, water and ethyl acetate) were used for investigation about antibacterial activity by disc diffusion method. The results showed that methanolic alcohol extract and fractions of C. longa L. rhizomes , C. myrrha L. gums showed biological activity against P. aeruginosa and S. aureus bacteria, but methanolic alcohol extract and fractions of G. biloba L. leaves product didn't show any activity as antibacterial substance. It can be concluded that the presence of secondary metabolites as flavonoids, alkaloids, tannins, glycosides and saponins in the plants under study would be marked a good anti-bacterial effect.
Global J Res. Med. Plants & Indigen. Med. | Volume 2, Issue 4 | April 2013 | 210–218
SCREENING FOR ANTIMICROBIAL ACTIVITY OF SOME PLANTS FROM SAUDI FOLK MEDICINE2013 •
The present investigation has been carried out to evaluate the antibacterial activity of ethanolic extracts of Acorus calamus rhizome, Alpinia galanga rhizome, Cinnamomum zeylanicum bark, Piper cubeba fruit, against two gram positive (Bacillus subtilis, Staphylococcus aureus) and two gram negative (Escherichia coli, Klebsiella pneumoniae) organisms respectively. Antibacterial activity was assessed by agar disc diffusion method. The activity of the extracts was measured by zone of inhibition and compared with a standard antibiotic Gentamicin. Among the various concentrations (50, 100, 150 µg/ml), 150µg/ml was found to be very effective. From the data of the results obtained in the present study, it can be concluded that, among the four plants selected, ethanol extracts of Acorus calamus and Alpinia galanga have given scopeful results against the microorganisms selected. Even though the extracts of Cinnamomum zeylanicum and Piper cubeba have antibacterial activity, at low concentration there was no appreciable activity.
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