Zusammenfassung
Zahlreiche Pflanzen setzen chemische Verbindungen mit giftiger bzw. toxischer Wirkung ein, um Fressfeinde oder anderweitige Schädlinge abzuwehren. Ist die toxische Wirkung der eingesetzten Verbindungen stark genug, kann die Pflanze auf den zusätzlichen Einsatz mechanischer Wehrkonzepte verzichten (Kap. 2 und 3).
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Literatur
Literatur zu Abschn. 4.1.1
Breitmaier E (2008) Alkaloide: Betäubungsmittel, Halluzinogene und andere Wirkstoffe, Leitstrukturen aus der Natur. Vieweg+Teubner, Wiesbaden. S 1–3
Hesse M (2000) Alkaloide - Fluch oder Segen der Natur? Wiley-VCH, Weinheim. S 7–10
Latscha HP, Kazmaier U (2008) Alkaloide. In: Latscha H P, Kazmaier U, Klein, HA (2016) (Hrsg) Chemie für Biologen (Bd 7), Springer. S 681–693
Meißner CFW (1819) Ueber ein neues Pflanzenalkali (Alkaloid). Schweiggers J Chem Phys 25:379–381
Pastore MN, Kalia YN, Horstmann M, Roberts MS (2015) Transdermal patches: history, development and pharmacology. Br J Pharmacol 172(9):2179–2209
Literatur zu Abschn. 4.1.1.1
Abbassy MA, El- OA, El-Hamady S, Sholo MA (1998) Insecticidal, acaricidal and synergistic effects of soosan, Pancratium maritimum extracts and constituents. J Egypt Soc Parasitol 28(1):197–205
Balogh A, Kretzschmar M (2007) Arzneimittel für Notfälle. In: Lemmer B, Brune K (Hrsg) Pharmakotherapie. Springer, S 537–542
Cozanitis DA, Friedmann T, Fürst S (1983) Study of the analgesic effects of galanthamine, a cholinesterase inhibitor. Arch Int Pharmacodyn Ther 266(2):229–238
Elgorashi EE, Stafford GI, van Staden J (2004) Acetylcholinesterase enzyme inhibitory effects of Amaryllidaceae alkaloids. Planta Med 70(03):260–262
Habermehl G, Ziemer P (1999) Abteilung Samenpflanzen, Unterabteilung Bedecktsamer. In: Mitteleuropäische Giftpflanzen und ihre Wirkstoffe. Springer, Berlin, S 45
Harvey AL (1995) The pharmacology of galanthamine and its analogues. Pharmacol Ther 68(1):113–128
Jaspersen-Schib R (1970) Toxic amaryllidaceas. Pharm Acta Helv 45(7):424–433
Jong ND, Vermeulen AM, Wijk RG, Groot HD (1998) Occupational allergy caused by flowers. Allergy 53(2):204–209
Ludewig R (1999) Akute Vergiftungen: Ratgeber zu Erkennung, Verlauf, Behandlung und Verhütung toxikologischer Notfälle. Wissenschaftliche Verlagsgesellschaft
Lüders G (1977) Die Narzissenkrankheit der Gärtner. In: Steigleder GK, Aulepp H (Hrsg) Verhandlungen der Deutschen Dermatologischen Gesellschaft. XXXI. Tagung, gehalten in Köln 29.03. – 02.04.1977. Der Hautarzt. Suppl II, 28. Jhrg, S 49–51
Neuwinger HD, Mebs D (1997) Boophone disticha. A hallucinogenic African plant. Dtsch. Apoth. Ztg. 137:1127–1132
Renard-Nozaki J, Kim T, Imakura Y, Kihara M, Kobayashi S (1989) Effect of alkaloids isolated from Amaryllidaceae on herpes simplex virus. Res Virol 140:115–128
Salarbaks AM (2009) Myocardial infarction and fatal heart arrest in elderly patients: 2 case reports. Reactions 1264:8
Sinclair C (2015) New warnings added to Reminyl prescribing information. Reactions 1579:5–28
Teuscher E (2010) Amaryllidaceenalkaloide. In: Teuscher E, Lindequist U (Hrsg) Biogene Gifte, Wissenschaftliche Verlagsgesellschaft, Stuttgart, S 517
Wildman WC (1960) Alkaloids of the Amaryllidaceae. In: Manske RHF (Hrsg) The alkaloids: chemistry and physiology. Academic Press, New York, Bd VI, S 289–413
Wilkinson D, Murray JI, Galantamine Research Group (2001) Galantamine: a randomized, double-blind, dose comparison in patients with Alzheimer’s disease. Int J Geriatr Psychiatry 16(9):852–857
Literatur zu Abschn. 4.1.1.2
Ahmed MS, Zhou DH, Maulik D, Eldefrawi ME (1990) Characterization of a cocaine binding protein in human placenta. Life Sci 46(8):553–561
Bandelow B (2013) Psychische und Verhaltensstörungen durch psychotrope Substanzen. In: Bandelow B, Gruber O, Falkai P (Hrsg) Kurzlehrbuch Psychiatrie. Springer, Berlin, S 38–48
Bogan R, Zimmermann T, Zilker T, Eyer F, Thiermann H (2009) Plasma level of atropine after accidental ingestion of Atropa belladonna. Clin Toxicol 47(6):602–604
Heard CM, Brain KR (1995) Does solute stereochemistry influence percutaneous penetration? Chirality 7(4):305–309
Jufer R, Walsh SL, Cone EJ, Sampson-Cone A (2006) Effect of repeated cocaine administration on detection times in oral fluid and urine. J Anal Toxicol 30(7):458–462
Lindequist U (2010) Tropanalkaloide. In: Teuscher E, Lindequist U (Hrsg) Biogene Gifte. Wissenschaftliche Verlagsgesellschaft, Stuttgart, S 599 ff.
Mulder PPJ, De Nijs M, Castellari M, Hortos M, MacDonald S, Crews C, Hajslova J, Stranska M (2016) Occurrence of tropane alkaloids in food. EFSA supporting publication. 13(12) 1140E. https://doi.org/10.2903/sp.efsa.2016. EN-1140. Zugegriffen: 6. Aug. 2019
Renner UD, Oertel R, Kirch W (2005) Pharmacokinetics and pharmacodynamics in clinical use of scopolamine. Ther Drug Monit 27(5):655–665
Roddick JG, Weissenberg M, Leonard AL (2001) Membrane disruption and enzyme inhibition by naturally-occurring and modified chacotriose-containing Solanum steroidal glycoalkaloids. Phytochemistry 56(6):603–610
Rogawski MA (1984) Transdermal scopolamine and sialorrhea. Arch Neurol 41(1):15–15
Seeger R, Neumann HP (1986) DAZ-Giftlexikon. Dtsch Apoth Ztg 126:1930
Trozak DJ (1985) Delayed hypersensitivity to scopolamine delivered by a transdermal device. J Am Acad Dermatol 13(2):247–251
United Nations (1977) Single Convention on Narcotic Drugs, 1961: As amended by the 1972 Protocol amending the Single Convention on Narcotic Drugs. 1961 UN https://www.unodc.org/pdf/convention_1961_en.pdf. Zugegriffen: 6. Aug. 2019
Literatur zu Abschn. 4.1.1.3
Adams HA, Flemming A (2014) Analgesie, Sedierung und Anästhesie in der Notfallmedizin. Aktuelles Wissen für Anästhesisten. Refresher Course Nr. 40, Mai 2014, Leipzig. https://www.ai-online.info/abstracts/pdf/dacAbstracts/2014/2014-015-RC105.1.pdf. Zugegriffen: 8. Febr. 2020
De Rosa G, Di Vincenzo G (1992) Isochelidonine, a benzophenanthridine alkaloid from Chelidonium majus. Phytochemistry 31(3):1085–1086
Frank DE (1946) The use of papaverine hydrochloride in the prevention of anaphylactic shock in guinea pigs. J Immunol 52:59–64
Fulde G, Wichtl M (1994) Analytik von Schöllkraut – das Hauptalkaloid ist Coptisin. Dtsch Apoth Ztg 134(12):17–22
Gemba M, Nakanishi JI, Mikuriya N, Nakajima M (1986) Influence of papaverine on cyclic nucleotide level and cellular metabolism in rat kidney cortex in terms of its inhibitory effect on p-aminohippurate transport. J Pharmacobiodyn 9(2):125–131
Lampert ML, Andenmatten C, Schaffner W (1998) Mahonia aquifolium (Pursh) Nutt. Z Phytotherapie 19:107–118
Lebiedzińska A, Szefer P (2006) Vitamins B in grain and cereal–grain food, soy-products and seeds. Food Chem 95(1):116–122
Kametani T, Honda T (1985) Synthetic method of narcotine. In: Manske RHF, Holmers HL (Hrsg) The alkaloids – chemistry and physiology, Bd 1 (1950) bis Band 63 (2006). Academic Press, New York
Kelentey B (1960) On the pharmacology of chelidonine and sanguinarine. Arzneimittel-Forschung, Editio Cantor Verlag, Aulendorf. 10. 135–137 https://europepmc.org/article/med/13853337. Zugegriffen: 9. Febr. 2020
Lindner E (1985) Structure activities and pharmacological properties of the opium alkaloids. In: The Chemistry and Biology of Isoquinoline Alkaloids, Springer, Berlin, S 38–46
Ludewig R (1999) Akute Vergiftungen. G Fischer, Jena
Menachery MD, Lavanier GL, Wetherly ML, Guinaudeau H, Shamma M (1986) Simple isoquinoline alkaloids. J Nat Prod 49(5):745–778
Nolting, DM (2005) Untersuchungen zur Zytotoxizität von Alkylanzien, Topoisomerasehemmstoffen und Ukrain auf vier humane Ewing-Sarkom-Zelllinien. Inaugural-Dissertation zur Erlangung der Doktorwürde der Medizinischen Fakultät Münster/Westfalen. https://d-nb.info/974230421/34. Zugegriffen: 9. Febr. 2020
Pitea M, Petcu P, Goina T, Preda N (1972) Thin-layer chromatographic studies of alkaloids from Berberis vulgaris. Planta Med 21(2):177–181
Sanwalka NJ, Khadilkar AV, Chiplonkar SA (2011) Development of non-dairy, calcium-rich vegetarian food products to improve calcium intake in vegetarian youth. Current Science, 657–663
Schneider W (1965) Methodology from the discovery to the synthesis of morphine. Mitt Dtsch Pharm Ges Pharm Ges DDR 35(5):85–90
Shukla S, Singh SP, Yadav HK, Chatterjee A (2006) Alkaloid spectrum of different germplasm lines in opium poppy (Papaver somniferum L.). Genet Resour Crop Evol 53(3):533–540
Schwarzmann-Schafhauser D (2005) Morphium. In: Gerabek WE, Haage BD, Keil G, Wegner W (Hrsg) Enzyklopädie Medizingeschichte. De Gruyter, Berlin, S 1009
Teuscher E (2010) Isochinolinalkaloide. In: Teuscher E, Lindequist U (Hrsg) Biogene Gifte. Wissenschaftliche Verlagsgesellschaft, Stuttgart, S 494
Wichtl M (2002) Chelidonii herba. Teedrogen und Psychopharmaka. Wissenschaftliche Verlagsgesellschaft, Stuttgart. S 130–134
Yi J, Ye X, Wang D, He K, Yang Y, Liu X, Li X (2013) Safety evaluation of main alkaloids from Rhizoma Coptidis. J Ethnopharmacol 145(1):303–310
Literatur zu Abschn. 4.1.1.4
Bevan-Jones R (2009) Poisonous plants: a cultural and social history. Windgather Press
Bisset NG (1981) Arrow poisons in China. Part II. Aconitum—botany, chemistry, and pharmacology. J Ethnopharmacol 4(3): 247–336
Boehm R, Serck J (1876) Beiträge zur Kenntnis der Alkaloide der Stephanskörner (Delphinium staphysagria). Arch Exp Pathol Pharmakol 5(4–5):311–328
Bruchhausen F v, Ebel S, Fram W, Hackenthal E (1991) Hagers Handbuch der pharmazeutischen Praxis. Bd. 7: Stoffe A–D. Birkhäuser/Springer, S 63
Chan TY (2009) Aconite poisoning. Clin Toxicol 47(4):279–285
Chan TY (2012) Aconite poisoning following the percutaneous absorption of Aconitum alkaloids. Forensic Sci Int 223(1–3):25–27
Chen Y, Koelliker S, Oehme M, Katz A (1999) Isolation of diterpenoid alkaloids from herb and flowers of aconitum napellus ssp. vulgare and electrospray ion trap multiple MS study of these alkaloids. J Nat Prod 62(5):798
Colombo ML, Bravin M, Tome F (1988) A study of the diterpene alkaloids of Aconitum napellus ssp. neomontanum during its onthogenetic cycle. Pharmacological research communications 20:123–128
Eibel WC, Otomura F, Pupulin ART (2014) Effect of Delphinium staphisagria in Murine Infection by Myocoptes musculinus. Br J Pharm Res 4(24):2702
Faugeras G, Paris R (1960) Aconite. III. Distribution of alkaloids in plants of various origins. Quantitative study. Toxicity. Annales pharmaceutiques francaises 18:474
Fühner, H. (1931). Akonitum-Vergiftung. (Giftmord). Arch Toxicol 2(1):123–124
Gubanow IA (1965) Delphinium als Quelle curareähnlicher Präparate. Planta Med 13(02):200–205
Jabbour F, Renner SS (2011) Consolida and Aconitella are an annual clade of Delphinium (Ranunculaceae) that diversified in the Mediterranean basin and the Irano-Turanian region. Taxon. Bd 60, Nr 4, S 1029–1040
Kozlov VA, Guliaeva TN (1983) Poisoning by the fruit of the privet (Ligustrum vulgare). Sud Med Ekspert 26(3):56
Liangqian L, Kadota Y (2001) Aconitum. In: Wu Zhengyi, Peter H. Raven, Deyuan Hong (Hrsg) Flora of China. Volume 6: Caryophyllaceae through Lardizabalaceae, Science Press und Missouri Botanical Garden Press, Beijing und St. Louis, ISBN 1-930723-05-9, S 149
Lin CC, Chan TY, Deng JF (May 2004) Clinical features and management of herb-induced aconitine poisoning. Ann Emerg Med 43(5):574–579
Ludewig R, Lohs K (1991) Akute Vergiftungen: Ratgeber für toxikologische Notfälle. Jena, Fischer. ISBN 3-334-00095-8
Macht DI (1938) The absorption of drugs and poisons through the skin and mucous membranes. J Am Med Assoc 110(6):409–414
Pelt JM (2005) Die Geheimnisse der Heilpflanzen, Knesebeck, ISBN 3-89660-291-8, S 80
Peura P (1982) Chemotaxonomic investigations of the alkaloids content in the genus Nuphar. I. Review of the literature. Acta Pharm Fenn 89:205–213
Puschner B, Booth MC, Tor ER, Odermatt A (2002) Diterpen Alkaloid Toxicosis in Cattle in the Swiss Alps. Vet Human Toxicol 44(1):8–10
Roth L (2012) Aconitum napellus. In: Roth L, Daunderer M, Kormann K (Hrsg) Giftpflanzen – Pflanzengifte. Nikol, S 88
Saisho K, Toyoda, M, Takagi, K, Satake M, Takahashi S, Yamamoto Y, Kasai K, Hashimoto S, Saito Y (1994) Identification of aconitine in raw honey that caused food poisoning. Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi) Japan 35(1):46–50_1
Serck J (1874) Beiträge zur Kenntnis des Delphinins in chemischer und physiologischer Beziehung. Inauguraldissertation. Kaiserliche Universität Dorpat (Estland). Druck von C. Matthiesen
Seeger R (1994) Aconitin und verwandte Diterpenalkaloide. Dtsch Apoth Ztg 134(29):2749
Tang L, Ye L, Lv C, Zheng Z, Gong Y, Liu Z (2011) Involvement of CYP3A4/5 and CYP2D6 in the metabolism of aconitine using human liver microsomes and recombinant CYP450 enzymes. Toxicol Lett 202(1):47–54. https://doi.org/10.1016/j.toxlet.2011.01.019.PMID21277363
Teuscher E (2010a) Terpenakaloide. In: Teuscher E, Lindequist U (Hrsg) Biogene Gifte. Wissenschaftliche Verlagsgesellschaft, Stuttgart, S 695 ff.
Teuscher E (2010b) Terpenakaloide. In: Teuscher E, Lindequist U (Hrsg) Biogene Gifte. Wissenschaftliche Verlagsgesellschaft, Stuttgart, S 706
Wink M, Van Wyk BE, Wink C (2008) Handbuch der giftigen und psychoaktiven Pflanzen. Wissenschaftliche Verlagsgesellschaft, Stuttgart, S 40
Zhang YT, Wu ZH, Zhang K, Zhao JH, Ye BN, Feng NP (2014) An in vitro and in vivo comparison of solid and liquid-oil cores in transdermal aconitine nanocarriers. J Pharm Sci 103(11):3602–3610
Literatur zu Abschn. 4.1.1.5, 4.1.1.5.1, 4.1.1.5.2, 4.1.1.5.3, 4.1.1.5.4
Akhtar S (2013) Areca nut chewing and esophageal squamous-cell carcinoma risk in Asians: A meta-analysis of case–control studies. Cancer Causes Control 24(2):257–265
Alpert HR, Connolly GN, Biener L (2012) A prospective cohort study challenging the effectiveness of population-based medical intervention for smoking cessation. Tobacco Control, tobaccocontrol-2011
Ambrose JA, Barua RS (2004) The pathophysiology of cigarette smoking and cardiovascular disease: an update. J Am Coll Cardiol 43(10):1731–1737
Amudhan MS, Begum VH, Hebbar, KB (2012) A review on phytochemical and pharmacological potential of Areca catechu L. seed. Int J Pharm Sci Res 3(11):4151
Arredondo J, Chernyavsky AI, Grando SA (2006) Nicotinic receptors mediate tumorigenic action of tobacco-derived nitrosamines on immortalized oral epithelial cells. Cancer Biol Ther 5(5):511–517
Benowitz NL, Burbank AD (2016) Cardiovascular toxicity of nicotine: Implications for electronic cigarette use. Trends Cardiovasc Med 26(6):515–523. https://doi.org/10.1016/j.tcm.2016.03.001.ISSN1050-1738.PMC4958544.PMID27079891
Audi J, Belson M, Patel M, Schier J, Osterloh J (2005) Ricin poisoning: a comprehensive review. Jama 294(18):2342–2351
Brown CJ, Cheng JM (2014) Electronic cigarettes: product characterization and design considerations. Tobacco Controll 23(2):ii4–ii10. https://doi.org/10.1136/tobaccocontrol-2013-051476. ISSN 0964-4563. PMC 3995271
British American Tobacco (2018) The global market. http://www.bat.com/group/sites/UK__9D9KCY.nsf/vwPagesWebLive/DO9DCKFM. Zugegriffen: 9. Sept. 2018
Chandra PS, Carey MP, Carey KB, Jairam KR (2003) Prevalence and correlates of areca nut use among psychiatric patients in India. Drug Alcohol Depend 69(3):311–316
Christen AG (1992) The impact of tobacco use and cessation on oral and dental diseases and conditions. Am J Med 93(1):25–31
Chu NS (2001) Effects of betel chewing on the central and autonomic nervous systems. J Biomed Sci 8(3):229–236
Davies P, Levy S, Pahari A, Martinez D (December 2001). Acute nicotine poisoning associated with a traditional remedy for eczema. Archives of Disease in Childhood 85(6):500–502. https://doi.org/10.1136/adc.85.6.500. PMC 1718993. PMID 11719343
Dawson RF, Solt ML, Christman DR (1960) Nicotine and its botanical sources. Ann N Y Acad Sci 90(1):7–12
Deng JF, Ger J, Tsai WJ, Kao WF, Yang CC (2001) Acute toxicities of betel nut: rare but probably overlooked events. J Toxicol Clin Toxicol 39(4), 355–360
Djurdjevac M, Trautner M (2003) Analyse von Nicotin aus Tabakblättern. https://www.chf.de/eduthek/projektarbeiten/trautner.pdf Zugegriffen: 8. Sept. 2018
Domino EF, Hornbach E, Demana T (1993) The nicotine content of common vegetables. (Letter to the editor) The New England Journal of Medicine. Bd 329, S 437. https://doi.org/10.1056/NEJM199308053290619
Fagerström KO (2011) Determinants of tobacco use and renaming the FTND to the Fagerström Test for Cigarette Dependence. Nicotine Tob Res 14(1):75–78
Fagerström KO, Bridgman K (2014) Tobacco harm reduction: the need for new products that can compete with cigarettes. Addict Behav 39(3):507–511. https://doi.org/10.1016/j.addbeh.2013.11.002
Faulkner JM (1933) Nicotine poisoning by absorption through the skin. J Am Med Assoc 100(21):1664–1665
Nair J, Ohshima H, Friesen M, Croisy A, Bhide SV, Bartsch H (1985) Tobacco-specific and betel nut-specific N-nitroso compounds: occurrence in saliva and urine of betel quid chewers and formation in vitro by nitrosation of betel quid. Carcinogenesis 6(2):295–303
Ferraz AC, Pereira LF, Ribeiro RL, Wolfman C, Medina JH, Scorza FA, Santos NF, Cavalheiro EA, Da Cunha C (2000) Ricinine-elicited seizures. A novel chemical model of convulsive seizures. Pharmacol Biochem Behav 65(4):577–83
Garg A, Chaturvedi P, Gupta PC (2014) A review of the systemic adverse effects of areca nut or betel nut. Indian J Med Paediatr Oncol: Official J Indian Soc Med Paediatr Oncol 35(1):3
Hamelin EI, Johnson RC, Osterloh JD, Howard DJ, Thomas JD (2012) Evaluation of ricinine, a ricin biomarker from a non-lethal castor bean ingestion. J Anal Toxicol 36(9):660–662. https://doi.org/10.1093/jat/bks077. PMC 4561852PMID 23014889
Herrmann K, Trinkkeller U (2014). Bewährte Rezepturen. Dermatologie und medizinische Kosmetik: Leitfaden für die kosmetische Praxis, Springer, S 215
Huang JL, McLeish MJ (1989) High-performance liquid chromatographic determination of the alkaloids in betel nut. J Chromatogr A 475(2):447–450
Northoff E (2004) Higher world tobacco use expected by 2010-growth rate slowing down. FAO News. Rome: Food and Agriculture Organization of the United Nations. https://www.un.org/press/en/2004/sag209.doc.htm. Zugegriffen: 8. Sept. 2018
Groß B, Landthaler M, Hohenleutner U (2003) Rauchen–Auswirkungen auf die Haut. JDDG: J Dtschen Dermatologischen Ges 1(10):801–810
Haustein KO, Groneberg D (2008) Tabakabhängigkeit: Gesundheitliche Schäden durch das Rauchen. Springer
Jeng JH, Chang MC, Hahn LJ (2001) Role of areca nut in betel quid-associated chemical carcinogenesis: current awareness and future perspectives. Oral oncology, 37(6), 477–492
Jimenez Ruiz CA, Solano Reina S, de Granda Orive JI, Signes-Costa Minaya J, de Higes Martinez E, Riesco Miranda JA, Altet Gómez N, Lorza Blasco JJ, Barrueco Ferrero M, de Lucas Ramos P (2014) „El cigarrillo electrónico. Declaración oficial de la Sociedad Española de Neumología y Cirugía Torácica (SEPAR) sobre la eficacia, seguridad y regulación de los cigarrillos electrónicos“. Archivos de Bronconeumología 50(8):362–367. https://doi.org/10.1016/j.arbres.2014.02.006. ISSN 0300-2896. PMID 24684764
Khan FA, Robinson PG, Warnakulasuriya KAAS, Newton JT, Gelbier S, Gibbons DE (2000) Predictors of tobacco and alcohol consumption and their relevance to oral cancer control amongst people from minority ethnic communities in the South Thames health region, England. J Oral Pathol Med 29(5):214–219
Knight, KG (Hrsg) (1985) Lloyd´s Survey Handbook. Lloyd’s of London Press Ltd., Colchester
McNeill A, Brose LS, Calder R, Hitchman SC, Hajek P, McRobbie H (August 2015) „E-cigarettes: an evidence update“ (PDF). Public Health England, UK, S 63
Lavoie FW, Harris TM (1991) Fatal nicotine ingestion. J Emerg Med 9(3):133–166. https://doi.org/10.1016/0736-4679(91)90318-a.PMID2050970
Lazutka FA, Vasilyauskene AD, Gefen SG (1969) Toxicological evaluation of the insecticide nicotine sulfate. Gig Sanit 34(5):30–33
Lee ST, Wildeboer K, Panter KE, Kem WR, Gardner DR, Molyneux RJ, Chang CW, Soti F, Pfister JA (2006) Relative toxicities and neuromuscular nicotinic receptor agonistic potencies of anaasine enantiomers and anabasine. Neurotoxicol Teratol 28(2):220–228. https://doi.org/10.1016/j.ntt.2005.12.010.PMID16488116
Le Houezec J (2003) Role of nicotine pharmacokinetics in nicotine addiction and nicotine replacement therapy: a review. Int J Tuberc Lung Dis 7(9):811–819
Ma YT, Hsu FL, Lan SJJ, Chen CF (1996) Tannins from betel nuts. J Chin Chem Soc 43(1):77–81
Mayer B (2013) How much nicotine kills a human? Tracking back the generally accepted lethal dose to dubious self-experiments in the nineteenth century. Arch Toxicol https://doi.org/10.1007/s00204-013-1127-0
McKnight RH, Spiller HA (2005) Green tobacco sickness in children and adolescents. Public health reports (Washington, D.C. 1974) 120(6):602–605 PMID 16350329, PMC 1497768
Miedaner T (2018) Tabak–der heilige Rauch. In: Genusspflanzen. Springer, Berlin, S 217–239
Minna JD (2003) Nicotine exposure and bronchial epithelial cell nicotinic acetylcholine receptor expression in the pathogenesis of lung cancer. J Clin Investig 111(1):31–33
Nutt D, King LA, Saulsbury W, Blakemore C (2007) Development of a rational scale to assess the harm of drugs of potential misuse. The Lancet 369(9566):1047–1053
Okamoto M, Kita T, Okuda H, Tanaka T, Nakashima T (Jul 1994) Effects of aging on acute toxicity of nicotine in rats. Pharmacol Toxicol 75(1):1–6. https://doi.org/10.1111/j.1600-0773.1994.tb00316.x. PMID 7971729. Zugegriffen: 8. Sept. 2018
Otmar G, Kotzias D (2007) Tobacco, Cigarettes and Cigarette Smoke, an Overview. Ispra, Italy: European Commission Joint Research Centre. Report No. EUR, 22783
Patel K, Patel DK (2016) Medicinal signifcance, pharmacological activities, and analytical aspects of ricinine: A concise report
Peng J, Cai S, Wang L, Zhao N, Zhang TJ, Chen ZX, Meng FH (2014) A metabonomic analysis of serum from rats treated with ricinine using ultra performance liquid chromatography coupled with mass spectrometry. Plos One 2014; 9(3):e90416
Proplanta (2009) Tabakanbaugebiete in Deutschland. https://www.proplanta.de/Fotos/Tabakanbaugebiete-in-Deutschland_Bild1160555615.html. Zugegriffen: 8. Sept. 2018
Rogers AJ, Denk LD, Wax PM (2004) Catastrophic brain injury after nicotine insecticide ingestion. The Journal of emergency medicine 26(2):169–172
Schep LJ, Slaughter RJ, Beasley DM (2009) Nicotinic plant poisoning. Clin Toxicol 47(8):771–781. https://doi.org/10.1080/15563650903252186.PMID19778187
Schuller HM, Orloff M (1998) Tobacco-specific carcinogenic nitrosamines: ligands for nicotinic acetylcholine receptors in human lung cancer cells. Biochem Pharmacol 55(9):1377–1384
Shetty KV, Johnson NW (1999) Knowledge, attitudes and beliefs of adult South Asians living in London regarding risk factors and signs for oral cancer. Community Dent Health 16(4):227–231
Shiffman S, Jarvik ME (1984) Cigarette smoking, physiological arousal, and emotional response: Nesbitt’s paradox re-examined. Addict Behav 9(1):95–98
Simons KW, Balls M (2001) Directive 2001/20/EC of the European Parliament and of the Council of 4 April 2001 on the Approximation of the Laws, Regulations and Administrative Provisions of the Member States Relating to the Implementation of Good Clinical Practice in The Conduct of Clinical Trials on Medicinal Products for Human Use. Official Journal of the European Communities 121:34–44
Sine C, Hrsg. (1993) Nicotine. In: Farm chemicals handbook 93:C245
Soave M (1895) Über Ricinin. Chemisches Zentralblatt 66, Bd I, S 853
Steenkamp PA, Van Heerden FR, Van Wyk BE (2002) Accidental fatal poisoning by Nicotiana glauca: identification of anabasine by high performance liquid chromatography/photodiode array/mass spectrometry. Forensic Sci Int 127(3):208–217
Villégier AS, Salomon L, Granon S, Changeux JP, Belluzzi JD, Lesli FM, Tassin JP (2006) Monoamine oxidase inhibitors allow locomotor and rewarding responses to nicotine. Neuropsychopharmacology 31(8):1704
Winstock AR, Trivedy CR, Warnakulasuriya KAAS, Peters TJ (2000) A dependency syndrome related to areca nut use: some medical and psychological aspects among areca nut users in the UK. Addiction Biol. 5:173–179
Warnakulasuriya S, Trivedy C, Peters TJ (2002) Areca nut use: an independent risk factor for oral cancer: The health problem is under-recognised. BMJ: Br Med J 324(7341):799
Warnakulasuriya S (2009) Global epidemiology of oral and oropharyngeal cancer. Oral Oncol 45(4–5):309–316
Wollina U, Verma S, Parikh D, Parikh A (2002) Orale und extraorale Erkrankungen durch BetelkauenOral and extraoral disease due to betel nut chewing. Der Hautarzt 53(12):795–797
Yamamoto I (1999) Nicotine to Nicotinoids: 1962 to 1997. In: Nicotinoid insecticides and the nicotinic acetylcholine receptor. Springer, Tokyo, S 3–27
Zhou XZ, Zhang JY, Zhao CY, Li JS, Zhan ZF, Li JY, Wang L (2007) Acute toxicity of arecoline hydrobromide in mice and rat in taking orally [J]. Prog Vet Med 9:008
Literatur zu Abschn. 4.1.1.6, 4.1.1.6.1, 4.1.1.6.2
Arnold RE (1978) Poisonous plants. Terra Pub
Bowman WC, Sanghvi IS (1963) Pharmacological actions of hemlock (Conium maculatum) alkaloids. J Pharm Pharmacol 15(1):1–25
Daugherty CG (1995) The death of Socrates and the toxicology of hemlock. Journal of medical biography 3(3):178–182
Davies ML, Davies TL (1994) Hemlock: murder before the Lord. Med Sci Law 34(4):331–333
Dekant W, Vamvakas S (2013) Giftpflanzen, Pflanzengifte. In: Aktories K, Förstermann U, Hofmann F, Starke K (Hrsg.) Allgemeine und spezielle Pharmakologie und Toxikologie, Elsevier, Urban & Fischer
Geiger PL (1833) Ueber einige neue giftige organische Alkalien. Annalen der Pharmacie 7(3):269–280
Lane JE (1920) A few early notes on syphilis in the english colonies of North America. Arch Dermatol Syphilology 2(2):215–219
Kursinszki L, Szőke É (2015) HPLC-ESI-MS/MS of brain neurotransmitter modulator lobeline and related piperidine alkaloids in Lobelia inflata L. J Mass Spectrom 50(5):727
Ramawat KG (1999) Secondary plant products in nature. Biotechnology Secondary Metabolities. Science Publishers, New Hampshire, S 123–143
Römpp-online (2002) Conium-Alkaloide. https://roempp.thieme.de/roempp4.0/do/data/RD-03-02437. Zugegriffen: 1. Okt. 2018
Schwarting AE (1963) Poisonous seeds and fruits. Progress in chemical toxicology 18:385–401
Speck FG (1937) Catawba medicines and curative practices. In: Davidson, DS (Hrsg) Publications of the Philadelphia Anthropological Society, Philadelphia. University of Pennsylvania Press, S 179–197
Stansbury J, Saunders PR, Zampieron ER (2013) The use of lobelia in the treatment of asthma and respiratory illness. J Restorative Med 2(1):94–100
Tamboli AM, Rub RA, Ghosh P, Bodhankar SL (2012) Antiepileptic activity of lobeline isolated from the leaf of Lobelia nicotiana efolia and its effect on brain GABA level in mice. Asian Pac J Trop Biomed 2(7):537–542
Weimann C, Heinrich M (1997) Indigenous medicinal plants in Mexico: the example of the Nahua (Sierra de Zongolica). Botanica Acta 110(1):62–72
Williamson EM (2017) Herbal neurotoxicity: An introduction to its occurrence and causes. In: Pelkonen O, Duez P, Vuorela P, Vuorela H (Hrsg) Toxicology of herbal products. Springer, Cham
Literatur zu Abschn. 4.1.1.7, 4.1.1.7.1, 4.1.1.7.2, 4.1.1.7.3, 4.1.1.7.4
Barceloux DG (2009) Potatoes, tomatoes, and solanine toxicity (Solanum tuberosum L., Solanum lycopersicum L.). Disease-a-month 55(6):391–402
Blumenthal M (Hrsg) (1998) The complete German Commission E Monographs: Therapeutic Guide to Herbal Medicine. Austin, TX, American Botanical Council, S 232
Börner H, Schlüter K, Aumann J (2009) Abwehrmechanismen der Pflanzen gegen Krankheitserreger und Schadtiere. Pflanzenkrankheiten und Pflanzenschutz, 357–382
Bös B (2016) Buxus. In: Giftpflanzen-Kompendium. http://www.giftpflanzen.com/buxus_sempervirens.html. Zugegriffen: 5. Febr. 2019
GIZ. Bonn (2018) Buchsbaum, immergrüner (Buxus sempervirens). http://www.gizbonn.de/74.0.html. Zugegriffen: 6. Okt. 2018
Haas HT (1938) Zur Pharmakologie des Germerins und seiner Spaltprodukte. Naunyn-Schmiedebergs Arch Exp Pathol Pharmakol 189(2–4):397–410
Hornfeldt CS, Collins JE (1990) Toxicity of nightshade berries (solanum dulcamara) in mice. J Toxicol Clin Toxicol 28(2):185–192
Hruby K, Lenz K, Krausler J (1981) Veratrum album poisoning (author’s transl). Wien Klin Wochenschr 93(16):517–519
lzawa K, Amino, Kohmura M, Ueda Y, Kuroda (2010) Bitter-Tasting Natural Products – Solanine. In: Mander L, Liu HW (Hrsg) Comprehensive natural products II: chemistry and biology (Bd 1) Elsevier, S 631–671
Jainu M, Devi CSS (2006) Antiulcerogenic and ulcer healing effects of Solanum nigrum (L.) on experimental ulcer models: possible mechanism for the inhibition of acid formation. J Ethnopharmacol 104(1–2):156–163
Leporatti ML, Ghedira K (2009) Comparative analysis of medicinal plants used in traditional medicine in Italy and Tunisia. J Ethnobiol Ethnomed 5(1):31
Ludewig R (1999) Akute Vergiftungen. Fischer, Jena
Morris SC, Lee TH (1984) The toxicity and teratogenicity of Solanaceae glycoalkaloids, particularly those of the potato (Solanum tuberosum): a review. Food Technology in Australia. http://agris.fao.org/agris-search/search.do?recordID=AU19850092379. Zugegriffen: 6. Aug. 2019
Patil BC, Sharma RP, Salunkhe DK, Salunkhe K (1972) Evaluation of solanine toxicity. Food and cosmetics toxicology 10(3):395–398
Roddick JG, Rijnenberg AL, Weissenberg M (1990) Membrane-disrupting properties of the steroidal glycoalkaloids solasonine and solamargine. Phytochemistry 29(5):1513–1518
Sander H (1963) Solanum dulcamara. VII. Biosynthesis of spirosolanol glycosides in the ripening fruit. In: Planta Med (11) 23
Taylor SL, Hefle SL (2017) Naturally occurring toxicants in foods. In Foodborne, S 327–344
Watzl B, Geisen R (2009) 22 Fragen zu Obst und Gemüse für die Praxis. Ernährungs-Umschau 56(6):22–24
Zitnak A, Johnston GR (1970) Glycoalkaloid content of B5141–6 potatoes. Am Potato J 47(7):256–260
Liteartur zu Abschn. 4.1.2
Kobayashi A, Matsumoto H (1965) Studies on methylazoxymethanol, the aglycone of cycasin: Isolation, biological, and chemical properties. Arch Biochem Biophys 110(2):373–380
Křen V (2008) Glycoside vs. aglycon: the role of glycosidic residue in biological activity. In: Glycoscience, Springer, Berlin, S 2589–2644
Minic Z (2008) Physiological roles of plant glycoside hydrolases. Planta 227(4):723
Reichstein T (1951) Chemie der herzaktiven Glykoside. Angew Chem 63(17–18):412–421
Literatur zu Abschn. 4.1.2.1
Caldwell JH, Greenberger NJ (1971) Interruption of the enterohepatic circulation of digitoxin by cholestyramine: I. Protection against lethal digitoxin intoxication. J Clin Investig 50(12):2626–2637
Smith TW, Butler jr, VP, Haber E, Fozzard H, Marcus FI, Bremner WF, Schulman IC, Phillips A (1982) Treatment of life-threatening digitalis intoxication with digoxin-specific Fab antibody fragments: experience in 26 cases. New England J Med 307(22):1357–1362
Literatur Abschn. 4.1.2.1.1
Freeman WT (1897) A note on the skin irritation caused by handling hyacinth bulbs. Br J Dermatol 9:66–67
Kamano Y, Kotake A, Hashima H, Inoue M, Morita H, Takeya K, Itokawa H, Nadachi N, Segawa T, Yukita A, Saitou K, Katsuyama M (1998) Structure–cytotoxic activity relationship for the toad poison bufadienolides. Bioorg Med Chem 6(7):1103–1115
Mendonça FS, Nascimento NC, Almeida VM, Braga TC, Ribeiro DP, Chaves HA, Silva Filho GB, Riet-Correa F (2018) An outbreak of poisoning by Kalanchoe blossfeldiana in cattle in northeastern Brazil. Trop Anim Health Prod 50(3):693–696
Petricic J, Tarle D, Holik L (1971) Über das Vorkommen des Hellebrins in den unterirdischen Teilen der Helleborus-Arten Jugoslawiens. Planta Medica 19 (S 01):143–146
Literatur zu Abschn. 4.1.2.1.2
Cassileth B (2010) Oleander (Nerium oleander). Oncology 24(13):1240–1240
Cui BN, Xu X, Zhao YS (2005) Clinical efficacy of compound periploca liquid in treating condyloma acuminatum and its effect on human papilloma virus DNA expression
Schmiedeberg O (1874) Untersuchungen über die pharmakologisch wirksamen Bestandtheile der Digitalis purpurea L. Arch Exp Pathol Pharmakol 3(1):16–43
Teuscher E (2010) Kap. 12 Steroide. In: Teuscher E, Lindequist U (Autoren) Biogene Gifte. Wissenschaftliche Verlagsgesellschaft, Stuttgart, S 229–280
Yarnell E (2015) Herbs against human papillomavirus. Altern Complement Ther 21(2):71–76
Literatur zu Abschn. 4.1.2.2, 4.1.2.2.1
Baker DA, Douglas Jr JM, Buntin DM, Micha JP, Beutner KR, Patsner B (1990) Topical podofilox for the treatment of condylomata acuminata in women. Obstet Gynecol 76(4), 656–659
Dewick PM, Jackson DE (1981) Cytotoxic lignans from Podophyllum, and the nomenclature of aryltetralin lignans. Phytochemistry 20(9):2277–2280
Drew SE, Conway SJ, Jennings P, Helliwell K (1987) Determination of the aryltetralin lignan content of podophyllum resins and roots/rhizomes. J Pharm Pharmacol 39(9): 738–739
Edwards A, Atma-Ram A, Thin RN (1988) Podophyllotoxin 0.5% v podophyllin 20% to treat penile warts. Sex Transm Infect 64(4):263–265
French L, Nashelsky J (2002) What is the most effective treatment for external genital warts? J Fam Pract 51(4):313
MacRae WD, Towers GN (1984) Biological activities of lignans. Phytochemistry 23(6):1207–1220
Peterson J, Dwyer J, Adlercreutz H, Scalbert A, Jacques P, McCullough ML (2010) Dietary lignans: physiology and potential for cardiovascular disease risk reduction. Nutr Rev 68(10):571–603
Podwyssotzki V (1880) Pharmakologische Studien über Podophyllum peltatum. Archiv für experimentelle Pathologie und Pharmakologie 13(1–2):29–52
Shu J, Hui S, Lihua W, Enping J, Dongxue C. Jianguang C, Xintian F (2011) Sedative and hypnotic effects of Schisandra Chinensis baill lignans. In: Human Health and Biomedical Engineering (HHBE), International Conference 2011, S 514–517
Sundharam JA (1990) Podophyllin and its use in the treatment of condylomata acuminata. Indian J Dermatol Venereol Leprol 56(1):10
Svindland HB (1984) Malignant transformation of condyloma acuminatum after treatment with podophyllin. Eur J Sex Transm Dis 1:165–167
Thiersch JB (1963) Effect of Podophyllin (P) and Podophyllotoxine (PT) on the Rat Litter in utero. Proc Soc Exp Biol Med 113(1):124–127
Wienert V (2004) Virus-induced anorectal diseases. Condylomata acuminata and herpes simplex. Der Hautarzt 55(3), 248–253
Literatur zu Abschn. 4.1.2.3
Eriksson G, Pliura A, Fernandez-Lopez J, Blanco Silva R, Villani F, Bucci G, Casasoli M, Cherubini M, Lauteri M, Mattioni C, Monteverdi C, Sansotta A, Garrod G, Mavrogiannis M, Scarpa R, Spalato F, Aravanoupoulos P, Alizoti E, Drouzas A (2004) Management of genetic resources of the multi-purpose tree species Castanea sativa Mill. In III Int Chestnut Congr 693:373–386
Hostettmann K (2005) Saponins. Cambridge University Press, S 18, ISBN 978-0-521-02017-6
Jagels R (1985) Health hazards of natural and introduced chemical components of boatbuilding woods. Am J Ind Med 8(3):241–251
Kerner J, Mitchell J, Maibach HI (1973) Irritant contact dermatitis from agave americana L: incorrect use of sap as hair restorer. Arch Dermatol 108(1):102–103
Kofler L (1927) Historischer Rückblick. In Die Saponine, Springer, Vienna, S 1–4
Lees DC, Lack HW, Rougerie R, Hernandez-Lopez A, Raus T, Avtzis ND, Augustin S, Lopez- C (2011) Tracking origins of invasive herbivores through herbaria and archival DNA: the case of the horse-chestnut leaf miner. Front Ecol Environ 9(6):322–328
Lüning HU, Schlösser E (1976) Die Rolle von Saponinen im Resistenzmechanismus gegen Pilze. Z Pflanzenkrankheiten Pflanzenschutz 83(6):317–327
Läuger P, Martin H, Müller P (1944) Über Konstitution und toxische Wirkung von natürlichen und neuen synthetischen insektentötenden Stoffen. Helv Chim Acta 27(1):892–928
Londoño VG, Villa SA, Medina LO, Valencia VA, Maya WC (2014) Spermicidal activity of steroidal and triterpenoid saponins extracted from various plants. Revista Cubana de Plantas Medicinales 19(1):76–84
Parmentier E (2012) Resistance of pearlfishes to saponins. In: Echinoderms in a Changing World: Proceedings of the 13th International Echinoderm Conference, January 5–9 2009, University of Tasmania, Hobart Tasmania, Australia. CRC Press, S 303
Sherrow V (2006) Encyclopedia of hair: a cultural history. Greenwood Publishing Group, S 286
Wagner G (2011) Waschmittel – Chemie, Umwelt, Nachhaltigkeit. Wiley, S 50
Literatur zu Abschn. 4.1.2.3.1
Brunner F, Hoffmann C, Schuller-Petrovic S (2001) Responsiveness of human varicose saphenous veins to vasoactive agents. Br J Clin Pharmacol 51(3):219–224
Gepdiremen A, Mshvildadze V, Süleyman H, Elias R (2005) Acute anti-inflammatory activity of four saponins isolated from ivy: alpha-hederin, hederasaponin-C, hederacolchiside-E and hederacolchiside-F in carrageenan-induced rat paw edema. Phytomedicine 12(6–7):440–444
Hofmann D, Hecker M, Völp A (2003) Efficacy of dry extract of ivy leaves in children with bronchial asthma–a review of randomized controlled trials. Phytomedicine 10(2–3):213–220
Sirtori CR (2001) Aescin: pharmacology, pharmacokinetics and therapeutic profile. Pharmacol Res 44(3):183–193
Spoerke DG, Spoerke SE, Hall A, Rumack BH (1987) Toxicity of Cyclamen persium (Mill). Vet Hum Toxicol 29(3):250–251
Rabe E, Pannier F, Ko A, Berboth G, Hoffmann B, Hertel S (2010) Incidence of varicose veins, chronic venous insufficiency, and progression of the disease in the Bonn Vein Study II. J Vasc Surg 51(3):791
Reznicek G, Jurenitsch J (1991) Der therapeutische Wert von Triterpensaponinen – Anspruch und Wirklichkeit. Pharm Unserer Zeit 20(6):278–281
Literatur zu Abschn. 4.1.2.3.2
Reich S, Altmeyer P, Stücker M (2006) Systemische medikamentöse Therapie von chronischen Venenerkrankungen – Systemic therapy of chronic venous diseases. Der Hautarzt 57(1):9–18
Literatur zu Abschn. 4.1.2.4
Anilkumar, M. (2010) 10. Ethnomedicinal plants as anti-inflammatory and analgesic agents. Ethnomedicine: A source of complementary therapeutics, 267–293
Bradley PR (1992) British Herbal Compendium Vol. I, British Herbal Medicine Association, 222
Chrubasik S, Eisenberg E, Balan E, Weinberger T, Luzzati R, Conradt C (2000) Treatment of low back pain exacerbations with willow bark extract: a randomized double-blind study. Am J Med 109(1):9–14
Schmid B, Tschirdewahn B, Kötter I, Günaydin I, Lüdtke R, Selbmann HK, Heide L (1998) Analgesic effects of willow bark extract in osteoarthritis: results of a clinical double-blind trial. Focus Altern Complement Ther 3(4):186
Schmid B, Kötter I, Heide L (2001) Pharmacokinetics of salicin after oral administration of a standardised willow bark extract. Eur J Clin Pharmacol 57(5):387–391
Sontakke S, Thawani V, Gharpure KJ, Patel SB (2005) Herbals in osteoarthritis, Milestone, 25
Vlachojannis J, Magora F, Chrubasik S (2011) Willow species and aspirin: different mechanism of actions. Phytotherapy Research 25(7):1102–1104
Literatur zu Abschn. 4.1.3
Kekulé A (1863) Terpene. In: Kekulé A (Autor) Lehrbuch der organischen Chemie. Ferdinand Enke, Erlangen. S 464–493
Mendoza- I, Kutzner E, Huber C, Segura J, Eisenreich W, Arrillaga I (2015) Metabolic cross-talk between pathways of terpenoid backbone biosynthesis in spike lavender. Plant Physiol Biochem 95:113–120
Literatur zu Abschn. 4.1.3.1
Breitmaier E (1999) Diterpene. In: Terpene. Vieweg + Teubner, Wiesbaden, S 60–89
Caesar GJ (53 v. Chr.) De bello Gallico. VI.Buch, 31, 5
Cowan MM (1999) Plant products as antimicrobial agents. Clin Microbiol Rev 12(4):564–582
Hecker E (1985) Cell membrane associated protein kinase C as receptor of diterpene ester co-carcinogens of the tumor promoter type and the phenotypic expression of tumors. Arzneimittelforschung 35(12A):1890–1903
Kedei N, Lundberg DJ, Toth A, Welburn P, Garfield SH, Blumberg PM (2004) Characterization of the interaction of ingenol 3-angelate with protein kinase C. Can Res 64(9):3243–3255
Keeling CI, Bohlmann J (2006) Diterpene resin acids in conifers. Phytochemistry 67(22):2415–2423
Kreibich G, Witte I, Hecker E (1971) On the biochemical mechanism of tumorigenesis in mouse skin. Z Krebsforschung und klinische Onkologie/Cancer Res Clin Oncol. Springer, Berlin, S 113–123
Lampe KF (1988) Rhododendrons, mountain laurel, and mad honey. JAMA 259(13):2009
Li L, Shukla S, Lee A, Garfield SH, Maloney DJ, Ambudkar SV, Yuspa SH (2010) The skin cancer chemotherapeutic agent ingenol-3-angelate (PEP005) is a substrate for the epidermal multidrug transporter (ABCB1) and targets tumor vasculature. Cancer research, 0008-5472
Maejima H, Kinoshita E, Seyama I, Yamaoka K (2003) Distinct sites regulating grayanotoxin binding and unbinding to D4S6 of Nav1. 4 sodium channel as revealed by improved estimation of toxin sensitivity. J Bio Chem
Reininger WR (2012) Phytansäure, eine beinahe übersehene verzweigtkettige Fettsäure in der menschlichen Ernährung. Diplomarbeit, Universität Wien, Fakultät für Lebenswissenschaften
Rosen RH, Gupta AK, Tyring SK (2012) Dual mechanism of action of ingenol mebutate gel for topical treatment of actinic keratoses: rapid lesion necrosis followed by lesion-specific immune response. J Am Acad Dermatol 66(3):486–493
Saraiva L, Fresco P, Pinto E, Portugal H, Gonçalves J (2001) Differential Activation by Daphnetoxin and Mezerein of PKC-Isotypes α, βI, δ and ζ. Planta Med 67(09):787–790
Szallasi A, Blumberg PM (1990) Resiniferatoxin and its analogs provide novel insights into the pharmacology of the vanilloid (capsaicin) receptor. Life Sci 47(16):1399–1408
Literatur zu Abschn. 4.1.3.1.1
U.S. National Plant Germplasm System (2017) Thymelaeaceae im Germplasm Resources Information Network (GRIN), USDA, ARS, National Genetic Resources Program. National Germplasm Resources Laboratory, Beltsville, Maryland. https://npgsweb.ars-grin.gov/gringlobal/taxonomyfamily.aspx?id=1126. Zugegriffen: 25. Nov. 2018
Literatur zu Abschn. 4.1.3.1.2
Bala TM, Panda M (2006) No poinsettia this Christmas. South Med J 99(7):772–774
Crowder JI, Sexton RR (1964) Keratoconjunctivitis resulting from the sap of candelebra cactus and the pencil tree. Arch Ophthalmol 72(4):476–484
Evens ZN, Stellpflug SJ (2012) Holiday plants with toxic misconceptions. W J Emerg Med 13(6):538
GIZ Bonn (2018) Weihnachtsstern (Euphorbia pulcherrima). http://www.gizbonn.de/245.0.html. Zugegriffen: 23. Dez. 2018
Gschwendt M, Hecker E (1974) Über die Wirkstoffe der Euphorbiaceen. J Cancer Res Clin Oncol 81(3):193–210
Hausen BM, Schulz, KH (1977) Occupational contact dermatitis due to Croton (Codiaeum variegatum (L.) A. Juss var. pictum (Lodd.) Muell. Arg.) Sensitization by plants of the Euphorbiaceae. Contact Dermatitis 3(6):289–292
Hausen BM (1988) Allergiepflanzen-Pflanzenallergene. Handbuch und Atlas der Allergie-induzierenden Wild- und Kulturpflanzen. Ecomed Landsberg, München
Hausen BM (1997) Euphorbia pulcherrima. in: Hausen BM, Vieluf I (Hrsg.) Allergiepflanzen-Pflanzenallergene. Handbuch und Atlas der Allergie-induzierenden Wild- und Kulturpflanzen. Kontaktallergene. Allergische Frühreaktionen. Ecomed, Landsberg a. Lech. S 129
Hecker E (1968) Cocarcinogenic principles from the seed oil of Croton tiglium and from other Euphorbiaceae. Can Res 28(11):2338–2348
Hecker E, Schmidt R (1974) Phorbolesters—the irritants and cocarcinogens of Croton Tiglium L. In: Fortschritte der Chemie Organischer Naturstoffe/Progress in the Chemistry of Organic Natural Products. Springer, Vienna, S 377–467
Krenzelok EP, Jacobsen TD, Aronis JM (1996) Poinsettia exposures have good outcomes… just as we thought. Am J Emerg Med 14(7):671–674
Machholz R, Lewerenz HJ (1989) Carbonsäuren. In: Machholz R Lewerenz HJ (Hrsg.) Lebensmitteltoxikologie. Springer Verlag, Berlin, Heidelberg. S 208–213
Mennel S, Müller C, Meyer CH (2005) Toxische Endophthalmitis. Der Ophthalmologe 102(11):1099–1101
Mizuno F, Osato T, Imai S, Koizumi S, Aya T, Kinoshita T, Hirai N, Hirota M, Ohigashi H, Koshimizu K (1986) Epstein-Barr virus-enhancing plant promoters in east Africa. AIDS research 2:151–155
NC State Extension (North Carolina State University) Raleigh, NC/USA (2016a) Euphorbia milii.https://plants.ces.ncsu.edu/plants/all/euphorbia-milii/. Zugegriffen: 25. Dez. 2018
NC State Extension (North Carolina State University) Raleigh, NC/USA (2016b) Euphorbia lactea. https://plants.ces.ncsu.edu/plants/all/euphorbia-lactea/. Zugegriffen: 25. Dez. 2018
Paulsen E, Skov PS, Andersen KE (1998) Immediate skin and mucosal symptoms from pot plants and vegetables in gardeners and greenhouse workers. Contact Dermatitis 39(4):166–170
Santucci B, Picardo M, Cristaudo A (1985) Contact dermatitis from Euphorbia pulcherrima. Contact dermatitis 12(5):285–286
Schmidt H, ØLholm‐Larsen P (1977) Allergic contact dermatitis from croton (Codiaeum). Contact dermatitis 3(2):100–100
U.S. National Plant Germplasm System (2017) Euphorbiaceae im Germplasm Resources Information Network (GRIN), USDA, ARS, National Genetic Resources Program. National Germplasm Resources Laboratory, Beltsville, Maryland. https://npgsweb.ars-grin.gov/gringlobal/taxonomyfamily.aspx?id=433. Zugegriffen: 25. Nov. 2018
Vincentz F (2006) Checklist: The succulent members of plant family Euphorbiaceae In: Sukkulente Euphorbien. https://dspace.jcu.cz/handle/123456789/12051. Zugegriffen: 25. Nov. 2018
Literatur zu Abschn. 4.1.3.2
Aiken C, Chen CH (2005) Betulinic acid derivatives as HIV-1 antivirals. Trends in molecular medicine 11(1):31–36
Blaschek W (1998) Iris. In: Blaschek W, Hänsel R, Keller K, Reichling J, Rimpler H, Schneider G (Hrsg.) Hagers Handbuch der pharmazeutischen Praxis. Drogen A-K. Springer, Berlin, Heidelberg. S 875–886. https://doi.org/10.1007/978-3-642-58928-7_9
Catchpole OJ, Grey JB, Noermark KA (2000) Fractionation of fish oils using supercritical CO2 and CO2+ ethanol mixtures. J Supercrit Fluids 19(1):25–37
Connolly JD, Hill RA (1991) Description of main terpenoid types. Dictionary of terpenoids 1:21–22
Drescher M, Bonakdar M (2001) Anreicherung des Kohlenwasserstoffes Squalen in einem Zwischenprodukt der Olivenölherstellung durch Extraktion mit verdichtetem Kohlendioxid. Chem Ing Tech 73(4):338–342
Fernandez-Arche A, Saenz MT, Arroyo M, De la Puerta R, Garcia MD (2010) Topical anti-inflammatory effect of tirucallol, a triterpene isolated from Euphorbia lactea latex. Phytomedicine 17(2):146–148
Fulda S, Kroemer G (2009) Targeting mitochondrial apoptosis by betulinic acid in human cancers. Drug Discov Today 14(17–18):885–890
Galgon T, Wohlrab W, Dräger B (2005) Betulinic acid induces apoptosis in skin cancer cells and differentiation in normal human keratinocytes. Exp Dermatol 14(10):736–743
Jäger S, Trojan H, Kopp T, Laszczyk MN, Scheffler A (2009) Pentacyclic triterpene distribution in various plants–rich sources for a new group of multi-potent plant extracts. Molecules 14(6):2016–2031
Jäger-Becker D (2009) Adjuvantien stärke Grippe-Impfstoffe. Ärzte Zeitung. https://www.aerztezeitung.de/medizin/krankheiten/infektionskrankheiten/influenza_grippe/article/565265/adjuvantien-staerken-grippe-impfstoffe.html. Zugegriffen: 26. Dez. 2019
Król SK, Kielbus M, Rivero-Müller A, Stepulak A (2015) Comprehensive review on betulin as a potent anticancer agent. BioMed Research International. Volume 2015. Article ID 584189. http://dx.doi.org/10.1155/2015/584189. Zugegriffen: 27. Dez. 2018
Langdon RG, Bloch, K (1953) The biosynthesis of squalene. J Biol Chem 200(1):129–134
Metelmann HR, Brandner JM, Schumann H, Bross F, Fimmers R, Böttger K, Scheffler A, Podmelle F (2015) Accelerated reepithelialization by triterpenes: proof of concept in the healing of surgical skin lesions. Skin Pharmacol Physiol 28:1–11
Pappas A (2009) Epidermal surface lipids. Dermato-endocrinology 1(2):72–76
Pisha E, Chai H, Lee IS, Chagwedera TE, Farnsworth NR, Cordell GA, Beecher CWW, Fong HHS, Kinghorn AD, Brown DM, Wani MC, Wall ME, Hieken TJ, Das Gupta TK, Pezzuto JM (1995) Discovery of betulinic acid as a selective inhibitor of human melanoma that functions by induction of apoptosis. Nat Med 1(10):1046–1051
Poralla K (1982) Considerations on the evolution of steroids as membrane components. FEMS Microbiol Lett 13(2):131–135
Ritter MC, Dempsey ME (1971) Specificity and role in cholesterol biosynthesis of a squalene and sterol carrier protein. J Biol Chem 246(5):1536–1539
Ríos JL, Escandell JM, Recio MC (2005) New insights into the bioactivity of cucurbitacins. In: Studies in Natural Products Chemistry. Vol. 32. Elsevier, Amsterdam, NL. S 429–469
Teuscher E (2010) Triterpene. In: Teuscher E, Lindequist U (Hrsg.) Biogene Amine. Wissenschaftliche Verlagsgesellschaft, Stuttgart. S 213
Tsujimoto M (1916) A highly unsaturated hydrocarbon in shark liver oil. Ind Eng Chem 8(10):889–896
Literatur zu Abschn. 4.1.3.2.1
Hartmann-Schreier J (2003) Cucurbitacine. In: Römpp Online. Georg Thieme. Zugegriffen: 21. Aug. 2018
Hylands PJ, Mansour ES, and Oskoui MT (1980) Bryocoumaric Acid, a New Triterpene from 80/o- nia dioica. Chem Soc Perkin Trans. I, 2933–2936
Krienke EG, von Mühlendahl KE (1978) Akzidentelle Vergiftungen durch Pflanzen, Teil III. Notfallmedizin 4:619
Metcalf RL, Metcalf RA, Rhodes AM (1980). Cucurbitacins as kairomones for diabroticite beetles. Proc Natl Acad Sci 77(7):3769–3772
Miro M (1995) Cucurbitacins and their pharmacological effects. Phytother Res 9(3):159–168
Ríos JL, Escandell JM, Recio MC (2005) New insights into the bioactivity of cucurbitacins. In: Studies in Natural Products Chemistry. Vol. 32. Elsevier, Amsterdam, NL. S 429–469
Teuscher E (2010) Triterpene. In: Teuscher E, Lindequist U (Hrsg.) Biogene Amine. Wissenschaftliche Verlagsgesellschaft, Stuttgart. S 215
Ukiya M, Akihisa T, Yasukawa K, Tokuda H, Toriumi M, Koike K, Kimura Y, Nikaido T, Aoi W, Nishino H. Takido M (2002) Anti-inflammatory and anti-tumor-promoting effects of cucurbitane glycosides from the roots of Bryonia dioica. J Nat Prod 65(2):179–183
Uzal FA, Puschner B, Tahara JM, Nordhausen RW (2005). Gossypol toxicosis in a dog consequent to ingestion of cottonseed bedding. J Vet Diagn Investig 17(6):626–629
von Mühlendahl KE (2003) Wichtigste giftige Beeren und Pflanzen. In: Mühlendahl, von KE, Oberdisse U, Bunjes R, Brockstedt M (Hrsg.) Vergiftungen im Kindesalter, Thieme, Stuttgart, S 5
Literatur zu Abschn. 4.1.3.2.2
Blaschek W (1998) Iris. In: Blaschek W, Hänsel R, Keller K, Reichling J, Rimpler H, Schneider G (Hrsg.) Hagers Handbuch der pharmazeutischen Praxis. Drogen A-K. Springer, Berlin, Heidelberg. S 875–886. https://doi.org/10.1007/978-3-642-58928-7_9
Christenhusz MJ, Byng JW (2016) The number of known plants species in the world and its annual increase. Phytotaxa 261(3):201–217. https://doi.org/10.11646/phytotaxa.261.3.1
Flückiger FA (1876) Ueber das Oel der Iriswurzel. Arch Pharm 208(6):481–487
Marner FJ, Jaenicke L (1989) Die absolute Konfiguration der Iridale und Cycloiridale unterschiedlicher Herkunft. Helv Chim Acta 72(2):287–294
Literatur Abschn. 4.1.4
Habermehl G, Ziemer P (1999) Abteilung Samenpflanzen, Unterabteilung Bedecktsamer. In: Mitteleuropäische Giftpflanzen und ihre Wirkstoffe. Springer, Berlin, S 45
Literatur Abschn. 4.1.4.1
Feng S, Zeng W, Luo F, Zhao J, Yang Z, Sun Q (2010) Antibacterial activity of organic acids in aqueous extracts from pine needles (Pinus massoniana Lamb.). Food Sci Biotechnol 19(1):35–41
Hänsel R (1968) Pflanzensäuren als Hauptwirkstoffe. In: Steinegger E, Hänsel R (Hrsg) Lehrbuch der allgemeinen Pharmakognosie, Springer, S 55–60
Literatur Abschn. 4.1.4.1.1
Braun R, Fuhrmann GF, Legrum W, Steffen C (2013) Spezielle Toxikologie für Chemiker: Eine Auswahl toxischer Substanzen. Springer, S 82
Kapur B M, Vandenbroucke AC, Adamchik Y, Lehotay DC, Carlen PL (2007) Formic acid, a novel metabolite of chronic ethanol abuse, causes neurotoxicity, which is prevented by folic acid. Alcohol: Clin Exp Res 31(12):2114–2120
Malizia E, Reale C, Pietropaoli P, De Ritis GC (1977) Formic acid intoxications. Acta pharmacologica et toxicologica 41:342
Malorny G (1969) Die akute und chronische Toxizität der Ameisensäure und ihrer Formiate. Z Ernährungswiss 9(4):332–339
Mcmartin KE, Collins TD (1983) Role of ethanol metabolism in the alcohol-induced increase in urinary folate excretion in rats. Biochem Pharmacol 32(17):2549–2555
Rajan N, Rahim R, Kumar SK (1985) Formic acid poisoning with suicidal intent: a report of 53 cases. Postgrad Med J 61(711):35–36
Sicherheitsdatenblatt (2016) Ameisensäure 85%. https://www.carlroth.com/downloads/sdb/de/5/SDB_5355_DE_DE.pdf. Zugegriffen: 30. Dez. 2018
Striepling E, Möller M, Bisgwa F, Rudolf KD (2008) Akzidentelle Verätzung mit Ameisensäure – Kasuistik und Literaturübersicht. GMS Verbrennungsmedizin; 2:Doc02. http://www.egms.de/static/en/journals/vmed/2008-2/vmed000003.shtml. Zugegriffen: 30. Dez. 2018
Thoms HFM, Holfert J, Mylius E, Gilg E, Jordan KF (1917) Schule der Pharmazie: Chemischer Theil. Springer
Literatur zu Abschn. 4.1.4.1.2
Charrier MJS, Savage GP, Vanhanen L (2002) Oxalate content and calcium binding capacity of tea and herbal teas. Asia Pac J Clin Nutr 11(4):298–301
Daunderer M (1995) Lexikon der Pflanzen-und Tiergifte: Diagnostik und Therapie. Nikol
Frohne D, Pfänder HJ (2004) Giftpflanzen. Ein Handbuch für Apotheker, Ärzte, Toxikologen und Biologen. Wissenschaftliche Verlagsgesellschaft, Stuttgart
Habermehl G, Ziemer P (1999) Abteilung Samenpflanzen, Unterabteilung Bedecktsamer. In: Mitteleuropäische Giftpflanzen und ihre Wirkstoffe, Springer, Berlin, S 217
Hess B, Zipperle L, Jaeger Ph (1993) Citrate and calcium effects on Tamm-Horsfall glycoprotein as a modifier of calcium oxalate crystal aggregation. Am J Physiol-Ren Physiol 265(6):F784–F791
Hönow R, Gu KLR, Hesse A, Siener R (2010) Oxalate content of green tea of different origin, quality, preparation and time of harvest. Urol Res 38(5):377–381
Isensee E (1844) Geschichte der Medicin, Chirurgie, Geburtshülfe, Staatsarzneikunde, Pharmacie und Naturwissenschaften und ihrer Litteratur: Buch 5: Neuere und neueste Geschichte der Heilwissenschaften und ihrer Litteratur (Pharmacie, Materia medica, Chirurgie, Ohren-, Augen-, Zahn-Heilkunde und Geburtshülfe) (Bd 2). Nauck
Libert B, Creed C (1985) Oxalate content of seventy-eight rhubarb cultivars and its relation to some other characters. J Hortic Sci 60(2):257–261
Littledike ET, James L, Cook H (1976) Oxalate (Halogeton) poisoning of sheep: certain physiopathologic changes. Am J Vet Res 37(6):661–666
Machholz R, Lewerenz HJ (1989) Carbonsäuren. In: Machholz R Lewerenz HJ (Hrsg.) Lebensmitteltoxikologie. Springer Verlag, Berlin, Heidelberg. S 208–213
Schweikart J (2013) Oxalat in Nahrung. https://www.oxalsaeure.net/oxalsaeurehaltige-lebensmittel/. Zugegriffen: 30. Dez. 2018
Noonan SC, Savage GP (1999) Oxalate content of foods and its effect on humans. Asia Pac J Clin Nutr 8(1): 64–74
Weiß C (2009) Oxalsäure, Ernährungs-Umschau 11, S 636–639
Wirth W, Gloxhuber C (1994) Toxikologie. Thieme, Stuttgart
Yang JC, Loewus FA (1975) Metabolic conversion of L-ascorbic acid to oxalic acid in oxalate-accumulating plants. Plant Physiol 56(2):283–285
Literatur zu Abschn. 4.1.4.2.1
Akbulut S, Semur H, Kose O, Ozhasenekler A, Celiktas M, Basbug M, Yagmur Y (2011) Phytocontact dermatitis due to Ranunculus arvensis mimicking burn injury: report of three cases and literature review. Int J Emerg Med 4(1):7
Basiner A (1882) Poisoning with oil of Ranunculus, Anemonin and Cardol. Am J Pharm 1835–1907:130
Bates N (2016) Acute plant poisoning in goats. Livestock 21(5):300–306
Bonora A, Dall’Olio G, Donini A, Bruni A (1987) An HPLC screening of some Italian Ranunculaceae for the lactone protoanemonin. Phytochemistry 26(8):2277–2279
Chao WGZ, Yuehuan W (1989) Studies on the extracts of three Ranunculaceae species and Protoanemonin for Bioassays. J Anhui Agric Univ 1:002
Christenhusz MJ, Byng JW (2016) The number of known plants species in the world and its annual increase. Phytotaxa 261(3):201–217
Degirmenci E, Duman N, Mat A, Bavunoglu I, Ikizceli I, Aktas C (2015) Phytocontact dermatitis: a case study/Fitokontakt Dermatit: Olgu Sunumu. Akademik Acil Tip Olgu Sunumlari Dergisi 6(3):66
Dombrowski S (2014) Plants and plant parts. In: Riedel F, Gründling F, Maslo R, Schlagintweit B, Schumann R, Stephan K, Woese K (Hrsg) List of Substances of the Competent Federal Government and Federal State Authorities. Bundesamt für Verbraucherschutz und Lebensmittelsicherheit. Springer, S 9–141
GIZ-Bonn.Zentrum für Kinderheilkunde.ukb (2018) Hahnenfuß Scharfer (Ranunculus acris). http://www.gizbonn.de/index.php?id=135. Zugegriffen: 7. Okt. 2018
Heinrich S (2008) Vorkommen von Giftpflanzen auf Wiesen und Weiden. Bakkalaureatsarbeit zur Erlangung der Würde einer Bakkalaurea der Naturwissenschaften. Veterinärmedizinischen Universität Wien und der Universität für Bodenkultur Wien. https://www.researchgate.net/profile/Silke_Schaumberger/publication/291945399_Vorkommen_von_Giftpflanzen_auf_Wiesen_und_Weiden_sowie_deren_Bedeutung_in_der_Pferdefutterung/links/56a9b11308ae7f592f0d9403.pdf
Hill R, Van Heyningen R (1951) Ranunculin: the precursor of the vesicant substance of the buttercup. Biochem J 49(3):332
Mares D (1987) Antimicrobial activity of protoanemonin, a lactone from ranunculaceous plants. Mycopathologia 98(3):133–140
Martín ML, San Román L, Domínguez A (1990) In vitro activity of protoanemonin, an antifungal agent. Planta Med 56(01):66–69
Moore RHS (1971) Poisoning by Old Man’s Beard (Clematis vitalba). Veterinary Record 89(21):569
Prieto JM, Recio MC, Giner RM, Máñez S, Rı́os (2003) Pharmacological approach to the pro-and anti-inflammatory effects of Ranunculus sceleratus L. J Ethnopharmacol 89(1):131–137
Takhtajan A (2009) Flowering plants. Springer. https://doi.org/10.1007/978-4020-9609-9
Teuscher E (2010) Herzwirksame Steroidglykoside. In: Teuscher E, Lindequist U (Autoren) Biogene Gifte, Wissenschaftl. Verlagsgesellschaft, Stuttgart, S 230
Turan H, Sarici M, Turan A (2012) Irritant phytocontact dermatitis due to buttercup (ranunculaceae) in a geriatric patient. Turkish Journal of Geriatrics, 15(4)
Ucmak D, Ayhan E, Meltem Z, Ucak H (2014) Presentation of three cases with phyto contact dermatitis caused by Ranunculus and Anthemis genera. J Dermatol Treat 25(6):467–469
Literatur zu Abschn. 4.2.1
Albrecht J, Wiesmann M (2006) Das olfaktorische System des Menschen. Der Nervenarzt 77(8):931–939
Christoph F (2001) Chemische Zusammensetzung und antimikrobielle Eigenschaften der ätherischen Öle von Leptospermum scoparium JR et G. Forst. und anderer Teebaumöle der Gattungen Kunzea, Leptospermum und Melaleuca unter besonderer Berücksichtigung von Handelsölen
EU-Verordnung (EG) Nr. 1907/2006 (REACH) über die Registrierung, Bewertung, Zulassung und Beschränkung von Chemikalien. Amtsblatt der Europäischen Union vom 29.05.2007. L136/129-L136/139. https://echa.europa.eu/de/regulations/reach/understanding-reach. Zugegriffen: 7. Jan. 2019
EU-Verordnung (EG) Nr. 1272/2008 über die Einstufung, Kennzeichnung und Verpackung von Stoffen und Gemischen. https://echa.europa.eu/de/web/guest/regulations/clp/legislation. Zugegriffen: 7. Jan. 2019
Engl A, Schmelzer A, Risch B (2018) Chemie Pur-Unterrichten in der Natur: Ätherischen Ölen auf der Spur. CHEMKON 25(1):7–15
Frings S, Müller F (2014) Riechen. In: Biologie der Sinne. Springer Spektrum, Berlin, S 95–116
Haagen-Smit AJ, Kisser JG (1958) The lower terpenes. In Der Stoffwechsel Sekundärer Pflanzenstoffe/The Metabolism of Secondary Plant Products. Springer, Berlin, S 52–131
Hänsel R (1968) Ätherische Öle, Harze und Balsame. In: Steinegger E, Hänsel R (Hrsg) Lehrbuch der Pharmakognosie – Auf phytochemischer Grundlage. Springer Berlin, S 407
Hagvall L, Bäcktorp C, Svensson S, Nyman G, Börje A, Karlberg AT (2007) Fragrance compound geraniol forms contact allergens on air exposure. Identification and quantification of oxidation products and effect on skin sensitization. Chem Res Toxicol 20(5):807–814
Heinrich J (2007) Das olfaktorische System beim Menschen: Der Einfluss von Gerüchen auf das Verhalten. (Examensarbeit 2006 im Fachbereich Biologie der Ernst Moritz Arndt Universität, Greifswald). GRIN
Legrum W (2011) Aromastoffe in Lebensmitteln. In Riechstoffe, zwischen Gestank und Duft, Vieweg + Teubner, S 83–116
Martin K, Allgaier C (2011) Wechselbeziehungen zwischen Pflanzen und Phytophagen. In Ökologie der Biozönosen. Springer, Berlin, S 27–70
Nagorka R, Straff W, Wolter E (2016) Duftstoffe. Produktspezifische Regelungen. Umweltbundesamt (Hrsg). Ratgeber Duftstoffe chemische Begleiter des Alltags. Broschüre
Passreiter CM (2009) Verwendung Ätherischer Öle in Phyto-und Aromatherapie. CME-Beitrag Pharmazeutische Wissenschaft. Apotheken-Magazin, 8–14
Reichling J, Gachnian-Mirtscheva R, Frater-Schröder M, Saller R, Rabinovich MI, Widmaier W (2008) Sekundäre Pflanzeninhaltsstoffe—phytochemische und phytopharmakologische Grundlagen. In: Heilpflanzenkunde für die Veterinärpraxis, S 33–39
Sattelberger R, Gauch H (2004) Humanbiomonitoring von Moschusduftstoffen. Endbericht an das Bundesministerium für Gesundheit und Frauen. BMGF, Wien
Sticher O (2007) Ätherische Öle und Drogen, die ätherisches Öl enthalten. In: Hänsel R, Sticher O (Hrsg) Pharmakognosie—Phytopharmazie Springer. Heidelberg, Berlin, S 1023–1140
Turek C, Stintzing FC (2013) Stability of essential oils: a review. Compr Rev Food Sci Food Saf 12(1):40–53
Verband Deutscher Riechstoffhersteller (2019) Duft erklären. http://duftstoffverband.de/dufterschaffen/musik-fuer-die-nase/. Zugegriffen: 8. Jan. 2019
Literatur zu Abschn. 4.2.1.1 :
Beer AM, Matreitz T (2013) Zur Anwendung ätherischer Öle im Krankenhaus. Zeitschrift für Phytotherapie, 34(04), 158–163
Demleitner M, Struck D (2011) Aromatherapie: Grundlagen, Wirkprinzipien, Praxis. Elsevier, Urban & Fischer Verlag, München
Hausen BM (1997) Teil I: Allergische Spätreaktionen in: Hausen BM, Vieluf I: Allergiepflanzen, Pflanzenallergene: Handbuch und Atlas der allergie-induzierenden Wild-und Kulturpflanzen: Kontaktallergene, allergische Frühreaktionen. ecomed, München, S 26–42
Kasanen, JP, Pasanen AL, Pasanen P, Liesivuori J, Kosma VM, Alarie Y (1999) Evaluation of sensory irritation of 3-carene and turpentine, and acceptable levels of monoterpenes in occupational and indoor environment. J Toxicoe. Br J Dermatol 156(3):510–515
Mücke W, Lemmen C (2010) Geruchsstoffe. In: Mücke W, Lemmen C (Hrsg.) Duft und Geruch: Wirkung und gesundheitliche Bedeutung von Geruchsstoffen. ecomed Medizin, Hüthe Jehling Rehm GmbH, München. S 54
Ross SA, ElSohly MA (1996) The volatile oil composition of fresh and air-dried buds of Cannabis sativa. J Nat Prod 59(1):49–51
Schnaubelt K, Pütz J (1995) Neue Aromatherapie. Egmont vgs-Verlagsgesellschaft, Köln
Literatur zu Abschn. 4.2.1.1.1
Allah MA, Foda YH, Saleh M, Zaki MSA, Mostafa MM (1975) Identification of the volatile constituents of the Egyptian lemongrass oil Part I. Gas chromatographic analysis. Food/Nahrung 19(3):195–200
Aschan O (1903) Die Konstitution des Kamphers und seiner wichtigsten Derivate: die theoretischen Ergebnisse der Kampherforschung monographisch Dargestellt. F. Vieweg und Sohn
Astani A, Reichling J, Schnitzler P (2010) Comparative study on the antiviral activity of selected monoterpenes derived from essential oils. Phytotherapy Res: Int J Devoted Pharmacol Toxicol Eval Nat Prod Deriv 24(5):673–679
Babu KG, Singh B, Joshi VP, Singh V (2002) Essential oil composition of Damask rose (Rosa damascena Mill.) distilled under different pressures and temperatures. Flavour Fragrance J 17(2):136–140
Badi HN, Yazdani D, Ali SM, Nazari F (2004) Effects of spacing and harvesting time on herbage yield and quality/quantity of oil in thyme, Thymus vulgaris L. Ind Crops Prod 19(3):231–236
Basch E, Ulbricht C, Hammerness P, Bevins A, Sollars D (2004) Thyme (Thymus vulgaris L.), thymol.J Herbal Pharmacother 4(1):49–67
Baydar H, Baydar NG (2005) The effects of harvest date, fermentation duration and Tween 20 treatment on essential oil content and composition of industrial oil rose (Rosa damascena Mill.). Industrial Crops and Products 21(2):251–255
Bayrak A, Akgül A (1994) Volatile oil composition of Turkish rose (Rosa damascena). J Sci Food Agric 64(4):441–448
Behr A, Johnen L (2009) Myrcene as a natural base chemical in sustainable chemistry: a critical review. ChemSusChem: Chemistry & Sustainability Energy & Materials 2(12):1072–1095
Berger RG (2012) Riechstoffe, zwischen Gestank und Duft. Vorkommen, Eigenschaften und Anwendung von Riechstoffen und deren Gemischen. In Legrum W (Hrsg) Angewandte Chemie 124(13):3112–3112
BG RCI (2000) Toxikologische Bewertung Nr.259 Thymol 06/00, BG Chemie. https://www.google.com/search?q=kontaktallergien+thymol. Zugegriffen: 11. Aug. 2019
Bickers D, Calow P, Greim H, Hanifin JM, Rogers AE, Saurat JH, Sipes IG, Smith RL, Tagami H (2003) A toxicologic and dermatologic assessment of linalool and related esters when used as fragrance ingredients. Food Chem Toxicol 41(7):919–942
Bleumink E, Mitchell JC, Nater JP (1973) Allergic contact dermatitis from cedar wood (Thuja plicata). Br J Dermatol 88(5):499–504
Bonamin F, Moraes TM, Dos Santos RC, Kushima H, Faria FM, Silva MA, Junior IV, Nogueira L, Bauab TM, Souza Brito ARM, da Rocha LR, Hiruma CA (2014) The effect of a minor constituent of essential oil from Citrus aurantium: The role of β-myrcene in preventing peptic ulcer disease. Chem Biol Interact 212:11–19
Bradberry SM, Cage SA, Proudfoot AT, Vale JA (2005) Poisoning due to pyrethroids. Toxicol Rev 24(2):93–106
Breitmeier E (1999) Terpene. Teubner Studienbücher. Stuttgart, Leipzig, S 21
Breitmeier E (2005) Terpene: Aromen, Düfte, Pharmaka, Pheromone: Aromen, Dufte, Pharmaka, Wiley VHC
Brito RG, Guimarães AG, Quintans JS, Santos MR, De Sousa DP, Badaue-Passos D Jr, de Lucca W, Jr BFA, Barreto EO, Oliveira AP, Quintans LJ (2012) Citronellol, a monoterpene alcohol, reduces nociceptive and inflammatory activities in rodents. J Nat Med 66(4):637–644
Caputi L, Aprea E (2011) Use of terpenoids as natural flavouring compounds in food industry. Recent Pat Food, Nutr & Agric 3(1):9–16
Chen W, Viljoen AM (2010) Geraniol—a review of a commercially important fragrance material. S Afr J Bot 76(4):643–651
Chialva F, Doglia G, Gabri G, Aime S, Milone L (1976) Isolamento et identificazione del cis-e trans-epocsiocimene nell'olio essenziale of Artemisia absinthium Linn. italiana. Riv. ital. essenze, profumi, piante offic., aromi, saponi, cosmet., aerozol, 58(10):522–526
Christensson JB, Andersen KE, Bruze M, Johansen JD, Garcia-Bravo B, Gimenez A, Goh CL, Nixon R, White IR (2012) Air-oxidized linalool–a frequent cause of fragrance contact allergy. Contact Dermatitis 67(5):247–259
Ciftci O, Ozdemir I, Tanyildizi S, Yildiz S, Oguzturk H (2011) Antioxidative effects of curcumin, β-myrcene and 1, 8-cineole against 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin-induced oxidative stress in rats liver. Toxicol Ind Health 27(5):447–453
Cole ER, Dos Santos RB, Lacerda V, Martins JDL, Greco SJ, Cunha Neto A (2014) Chemical composition of essential oil from ripe fruit of Schinus terebinthifolius Raddi and evaluation of its activity against wild strains of hospital origin. Brazilian J Microbiol 45(3):821–828
Daphi J, Raddatz H, Müller R (2010) Untersuchung von Riechstoffen-Kontrollierte Düfte. HighChem-Aktuelles aus der Lebensmittelchemie 5:94–95
Diepgen TL, Dickel H, Becker D, Geier J, Mahler V, Schmidt A, Schwanitz HJ †, Skudlik C, Wagner E, Wehrmann W, Weisshaar E, Werfel T, Blome O (2005) Evidenzbasierte Beurteilung der Auswirkung von Typ-IV-Allergien bei der Minderung der Erwerbsfähigkeit (Evidence-based evaluation of the occupational relevance of different delayed type sensitizations or allergens) Der Hautarzt, 56(3):207–223
Elumalai S, Kesavan R, Ramganesh S, Murugesan R (2011) Isolation, purification and identification of the anti-diabetic components from Cinnamomum zeylanicum and Cinnamomum cassia bark oil extracts. Current Botany
Eriksson KA, Stjernberg NL, Levin JO, Hammarström U, Ledin MC (1996) Terpene exposure and respiratory effects among sawmill workers. Scand J Work Environ Health 22:182–190
Fretz TA, Sydnor TD, Cobbs MR (1976) Monoterpene composition of foliage of 9 Juniperus species. Sci Hortic 5(1):85–91
Gershenzon J, Croteau R (1990) Regulation of monoterpene biosynthesis in higher plants. In Biochemistry of the mevalonic acid pathway to terpenoids. Springer, Boston, MA. S 99–160
Gessner O, Orzechowski G (1974) Die Giftpflanzen und Arzneipflanzen von Mitteleuropa. Universitätsverlag Winter
Grosse Y, Loomis D, Guyton KZ, Ghissassi FEl, Bouvard V, Benbrahim-Tallaa L, Mattock H, Straif K and Monograph Working Group (2017) Some chemicals that cause tumours of the urinary tract in rodents. Lancet Oncol 18(8):1003
Gurova AI, Grinina OV, Smoliar N, Drozhzhina NA, Zasorina IN (1986) Evaluation of the toxicity of chrysanthemic acid and its derivatives. Gig Sanit 1:16–18
Hagvall L, Bäcktorp C, Svensson S, Nyman G, Börje A, Karlberg AT (2007) Fragrance compound geraniol forms contact allergens on air exposure. Identification and quantification of oxidation products and effect on skin sensitization. Chem Res Toxicol 20(5):807–814
Hartmann-Schreier J (2003) Citronellole. In: Römpp- online Lexikon Chemie. Thieme. https://roempp.thieme.de/roempp4.0/do/data/RD-03-01937. Zugegriffen: 20. Jan. 2019
Hartmann-Schreier J, Menzel M (2010) Geraniol. In: Römpp-online Lexikon Chemie. Thieme. https://roempp.thieme.de/roempp4.0/do/data/RD-07-00782. Zugegriffen: 20. Jan. 2019
Hausen BM, Reichling J, Harkenthal M (1999) Degradation products of monoterpenes are the sensitizing agents in tea tree oil. Am J Contact Dermatitis 10(2):68–77
Hausen BM, Kuhlwein A, Schulz KH (1982) Colophony allergy. A contribution to the origin, chemistry, and uses of colophony and modified colophony products, 1. Dermatosen in Beruf und Umwelt. Occupation and environment 30(4):107–115
Hausen BM (1997) Teil I: Allergische Spätreaktionen. in: Hausen BM, Vieluf I (Hrsg.): Allergiepflanzen, Pflanzenallergene: Handbuch und Atlas der allergie-induzierenden Wild-und Kulturpflanzen: Kontaktallergene, allergische Frühreaktionen. ecomed, Landsberg a. Lech. S 26–42
Heydorn S, Menne T, Andersen KE, Bruze M, Svedman C, White IR, Basketter DA (2003) Citral a fragrance allergen and irritant. Contact dermatitis 49(1):32–36
Holopainen M, Hiltunen R, von Schantz M (1987) A study on tansy chemotypes. Planta Med 53(03):284–287
Holzmann, G., Wangelin, M., & Bruns, R. (2012). Chemische Grundlagen zu den Baustoffen. In Natürliche und pflanzliche Baustoffe, Vieweg+ Teubner, S 25–53
Inui T, Tsuchiya F, Ishimaru M, Oka K, Komura H (2013) Different beers with different hops. Relevant compounds for their aroma characteristics. J Agric Food Chem 61(20):4758–4764
Inouye S, Uchida K, Yamaguchi H (2001) In-vitro and in-vivo anti-Trichophyton activity of essential oils by vapour contact. Mycoses 44(3–4):99–107
Jonas M (2018) Charakterisierung geruchsaktiver und physiologisch aktiver Aromastoffe in Salbei und Rosmarin (Dissertation, Technische Universität München)
Jost M, Rüegger M, Gutzwiller A, Liechti B, Wolf R (2003) Verhütung von Berufskrankheiten in pathologisch-anatomischen Instituten und histologischen Laboratorien. Suva. S 19. http://www.sohf.ch/Themes/Labo/2869_25_D.pdf. Zugegriffen: 13. Jan. 2019
Jouhar AJ (1991) Poucher's Perfumes, cosmetics and soaps. Vol.1 The Raw Materials of Perfumery. Chapman and Hall, London
Juergens UR, Dethlefsen U, Steinkamp G, Gillissen A, Repges R, Vetter H (2003) Anti-inflammatory activity of 1.8-cineol (eucalyptol) in bronchial asthma: a double-blind placebo-controlled trial. Respir Med 97(3):250–256
Karlberg AT, Börje A, Duus J, Lidén C, Rastogi S, Roberts D, Uter W, White IR (2013) Activation of non-sensitizing or low-sensitizing fragrance substances into potent sensitizers–prehaptens and prohaptens. Contact Dermatitis 69(6):323–334
Karlberg AT, Börje A, Duus Johansen J, Lidén C, Rastogi S, Roberts D, Uter W, White IR (2013) Activation of non‐sensitizing or low‐sensitizing fragrance substances into potent sensitizers–prehaptens and prohaptens. Contact Dermatitis 69(6):323–334
Kawashima K, Miwa Y, Kimura M, Mizutani K, Hayashi A, Tanaka O (1985) Diuretic action of paeonol. Planta Med 51(03):187–189
Kofidis G, Bosabalidis A, Kokkini S (2004) Seasonal variation of essential oils in a linalool-rich chemotype of Mentha spicata grown wild in Greece. J Essent Oil Res 16(5):469–472
Kusumi T, Uchida H, Inouye Y, Ishitsuka M, Yamamoto H, Kakisawa H (1987) Novel cytotoxic monoterpenes having a halogenated tetrahydropyran from Aplysia kurodai. J Org Chem 52(20):4597–4600
Lee TY, Lam TH (1989) Irritant contact dermatitis due to the herbal oil, Black Man Oil. Contact Dermatitis 20(3):229–230
Li J, Jongsma MA, Wang CY (2014) Comparative analysis of pyrethrin content improvement by mass selection, family selection and polycross in pyrethrum [Tanacetum cinerariifolium (Trevir.) Sch. Bip.] populations. Ind Crops Prod 53:268–273
Ludewig R (1999) Akute Vergiftungen. Fischer, Jena
Mabberly DJ (1997) The plant book. A portable dictionary of the vascular plants. Cambridge University Press
Malkiewicz K, Andersson L (2015) Stoffbewertung für Citronellal. Co RAP (Community rolling action plan) https://echa.europa.eu/de/information-on-chemicals/evaluation/community-rolling-action-plan/corap-table/-/dislist/details/0b0236e1807e8de0 Zugegriffen: 20. Jan. 2019
Marchese A, Orhan IE, Daglia M, Barbieri R, Di Lorenzo A, Nabavi SF, Gortzi O, Izadi M, Nabavi SM (2016) Antibacterial and antifungal activities of thymol: a brief review of the literature. Food Chem 210:402–414
Marongiu B, Piras A, Porcedda S (2004) Comparative analysis of the oil and supercritical CO2 extract of Elettaria cardamomum (L.) Maton. J Agric Food Chem 52(20):6278–6282
Matura M, Goossens A, Bordalo O, Garcia-Bravo B, Magnussona K, Wrangsjö K, Karlberg AT (2002) Oxidized citrus oil (R-limonene): a frequent skin sensitizer in Europe. J Am Acad Dermatol 47(5):709–714
Matura M, Sköld M, Börje A, Andersen KE, Bruze M, Frosch P, Goossenns A, Johansen JD, Svedman C, White IR, Karlberg AT (2005) Selected oxidized fragrance terpenes are common contact allergens. Contact Dermatitis 52(6):320–328
Menzel M (2009) Linalool. In: Römpp-online Lexikon Chemie. Thieme. https://roempp.thieme.de/roempp4.0/do/data/RD-12-01184. Zugegriffen: 20. Jan. 2019
Merck (2010) Myrcen. Sicherheitsdatenblatt gemäß Verordnung (EG) Nr. 1907/2006. Sicherheitsdatenblatt – Merck Millipore (PDF). Zugegriffen: 11. Aug. 2019
Mersch-Sundermann V (2007) Gesundheitliche Bewertung von alpha-Pinen in der Innenraumluft-aktueller Erkenntnisstand. Umweltmedizin in Forschung und Praxis 12(3):129
Montag A (1997) Bedarfsgegenstände: Recht-Technologie-Chemie-Wechselwirkungen; Eine Einführung. (unter Mitwirkung von Andreas Montag) Behr’s Verlag, Hamburg
Möschlin S (1986) Klinik und Therapie der Vergiftungen
Nagtegaal MJ, Pentinga SE, Kuik J, Kezic S, Rustemeyer T (2012) The role of the skin irritation response in polysensitization to fragrances. Contact dermatitis 67(1):28–35
Nhu TT, Casabianca H, Grenier-Loustalot MF (2006) Deuterium/hydrogen ratio analysis of thymol, carvacrol, γ-terpinene and p-cymene in thyme, savory and oregano essential oils by gas chromatography–pyrolysis–isotope ratio mass spectrometry. J Chromatogr A 1132(1–2):219–227
Nielsen GD, Larsen ST, Larsen ST, Hougaard KS, Hammer M, Wolkoff P, Clausenn PA, Wilkins CK, Alarie Y (2005) Mechanisms of acute inhalation of (+) and (–)-α-Pinene in BALB/c mice. Basic Clin Pharmacol Toxicol 96:420–428
Pascual TJ de, Barrero A, Caballero A, Caballero M, San Feliciano A (1978) Components of berries of Juniperus sabina L hydrocarbons of essential oil. In: Anales de Quimica 74(7–8):1093–1096
Pelkonen O, Abass K, Wiesner J (2013) Thujone and thujone-containing herbal medicinal and botanical products: Toxicological assessment. Regul Toxicol Pharmacol 65(1):100–107
Penagos H, Manuskiatti W, Abrams K, Hogan DJ, Maibach HI, O’Malley M (2001) The reported skin effects of pesticides by use and structural category. In: Penagos H, O’Malley M, Maibach HI (Hrsg) Pesticide Dermatoses. CRC Press, Boca Raton, S 102
Peterson A, Machmudah S, Roy BC, Goto M, Sasaki M, Hirose T (2006) Extraction of essential oil from geranium (Pelargonium graveolens) with supercritical carbon dioxide. J Chem Tech Biotechnol: Int Res Process, Environ Clean Technol 81(2):167–172
Pfalzgraf A, Rohn S (2015) Bedarfsgegenstände: Materialien – Chemie – Wechselwirkungen – Konformität. Behr’s Verlag
Pitarević I, Kuftinec J, Blažević N, Kuštrak D (1984) Seasonal variation of essential oil yield and composition of dalmatian sage, Salvia officinalis. J Nat Prod 47(3):409–412
Raina VK, Srivastava SK, Aggarwal KK, Syamasundar KV, Khanuja SPS (2003) Essential oil composition of Cymbopogon martinii from different places in India. Flavour Fragr J 18(4):312–315
Rapp A, Suckrau I, Versini G (1993) Untersuchungen des Trauben-und Weinaromas. Z Lebensmitteluntersuchung Forsch A 197(3):249–254
Sacchetti G, Maietti S, Muzzoli M, Scaglianti M, Manfredini S, Radice M, Bruni R (2005) Comparative evaluation of 11 essential oils of different origin as functional antioxidants, antiradicals and antimicrobials in foods. Food Chem 91(4):621–632
Sacco T, Chialva F (1988) Chemical characteristics of the oil from Artemisia absinthium collected in Patagony (Argentina). Planta Med 54(01):93–93
Satar S (1984) Single and double terpenes in etheric oil of Mongolian juniper type. Pharmazie 39(1):66
SCCS (2012) How can fragrance substance become skin allergens. https://ec.europa.eu/health/scientific_committees/opinions_layman/perfume-allergies/en/l-3/3-becoming-allergens.htm. Zugegriffen: 11. Aug. 2019
Schiller KH (2002) Wirkungen von Zubereitungen aus Humulus lupulus L. in pharmakologischen Modellen. Mathematisch-Naturwissenschaftliche Fakultät, Westfälische Wilhelms-Universität Münster. Dissertation, S 1–155. https://d-nb.info/967390389/34. Zugegriffen: 11. Aug. 2019
Sezik E, Yeşilada E, Honda G, Takaishi Y, Takeda Y, Tanaka T (2001) Traditional medicine in Turkey X. Folk medicine in central Anatolia. J Ethnopharmacol, 75(2–3):95–115
Shafer TJ, Meyer DA (2004) Effects of pyrethroids on voltage-sensitive calcium channels: a critical evaluation of strengths, weaknesses, data needs, and relationship to assessment of cumulative neurotoxicity. Toxicol Appl Pharmacol 196(2):303–318
Shafer TJ, Meyer DA, Crofton KM (2004) Developmental neurotoxicity of pyrethroid insecticides: critical review and future research needs. Environ Health Perspect 113(2):123–136
Shaw PE (1979) Review of quantitative analyses of citrus essential oils. J Agric Food Chem 27(2):246–257
Silva AB, Silva T, Franco ES, Rabelo SA, Lima ER, Mota RA, Da Camara CAG, Pontes-Filho T, Lima-Filho JV (2010) Antibacterial activity, chemical composition, and cytotoxicity of leaf’s essential oil from Brazilian pepper tree (Schinus terebinthifolius, Raddi). Braz J Microbiol 41(1):158–163
Soran ML, Varodi C, Cobzac SC, Lung I (2011) Essentials oils determination from Satureja hortensis L. by chromatographic techniques. J Essent Oil Bearing Plants 14(6):699–707
Sulman E, Matveeva V, Doluda V, Nicoshvili L, Bronstein L, Valetsky P, Tsvetkova I (2006) Nanostructured catalysts for the synthesis of vitamin intermediate products. Top Catal 39(3–4):187–190
Tetenyi P, Kaposi P, Hethelyi E (1975) Variations in the essential oils of Tanacetum vulgare. Phytochemistry 14(7):1539–1544
Tornier C, Rosdy M, Maibach HI (2006) In vitro skin irritation testing on reconstituted human epidermis: reproducibility for 50 chemicals tested with two protocols. Toxicol In Vitro 20(4):401–416
Treudler R, Richter G, Geier J, Schnuch A, Orfanos CE, Tebbe B (2000) Increase in sensitization to oil of turpentine: recent data from a Multicenter Study on 45,005 patients from the German-Austrian Information Network of Departments of Dermatology (IVDK). Contact Dermatitis 42(2):68–73
Vilaplana J, Romaguera C (2000) Allergic contact dermatitis due to eucalyptol in an anti-inflammatory cream. Contact Dermatitis 43(2):118
Vostrowsky O, Brosche T, Ihm H, Zintl R, Knobloch K (1981) On the essential oil components in Artemisia absinthium. Z Naturforsch 36:369–377
Yatagai M, Sato T, Takahashi T (1985) Terpenes of leaf oils from Cupressaceae. Biochem Syst Ecol 13(4):377–385
Zeković ZP, Lepojević ZD, Mujić IO (2009) Laurel extracts obtained by steam distillation, supercritical fluid and solvent extraction. J Nat Prod 2:104–109
Literatur zu Abschn. 4.2.1.1.2
Drew DP, Krichau N, Reichwald K, Simonsen HT (2009) Guaianolides in apiaceae: perspectives on pharmacology and biosynthesis. Phytochem Rev 8(3):581–599
Park SH, Choi SU, Lee CO, Yoo SE, Yoon SK, Kim YK, Ryu SY (2001) Costunolide, a sesquiterpene from the stem bark of Magnolia sieboldii, inhibits the RAS-farnesyl-proteintransferase. Planta Med 67(04):358–359
Picman AK (1986) Biological activities of sesquiterpene lactones. Biochem Syst Ecol 14(3):255–281
Pittayakhajonwut P, Usuwan A, Intaraudom C, Veeranondha S, Srikitikulchai P (2009) Sesquiterpene lactone 12, 8-eudesmanolides from the fungus Xylaria ianthinovelutina. Planta Med 75(13):1431–1435
Schmidt TJ (2006) Structure-activity relationships of sesquiterpene lactones. In Studies in natural products chemistry Elsevier (33), S 309–392
Warshaw EM, Zug KA (1996) Sesquiterpene lactone allergy. American journal of contact dermatitis 7(1):1–23
Wedge DE, Galindo JCG, Macıas FA (2000) Fungicidal activity of natural and synthetic sesquiterpene lactone analogs. Phytochemistry 53(7):747–757
Literatur zu Abschn. 4.2.1.2.1
Hartmann-Schreier J (2017) Anethol. In: Römpp – Lexikon der Chemie. https://roempp.thieme.de/roempp4.0/do/data/RD-01-02415. Zugegriffen: 25. Jan. 2019
Poon TS, Freeman S (2006) Cheilitis caused by contact allergy to anethole in spearmint flavoured toothpaste. Australas J Dermatol 47(4):300–301
Reichling J, Suschke U, Schneele J, Geiss HK (2006) Antibacterial activity and irritation potential of selected essential oil components–structure-activity relationship. Nat Prod Commun 1(11):1934578X0600101116.
Schnaubelt K (1995) Neue Aromatherapie. Pütz J (Hrsg) Egmont vgs-Verlagsgesellschaft
Literatur zu Abschn. 4.2.1.2.2
Badr AN, Nada F, Shehata MG, Amra HA, Jones HC, Chancey JC, Oguz H (1980) Dillapiol and Apiol as Specific Inhibitors of the Biosynthesis of Aflatoxin G1 in Aspergillus parasiticus. J Appl Sci 17(4):67–73
Baltes W (2007) Gesundheitsschädliche Stoffe in natürlichen Lebensmitteln. Lebensmittelchemie. Springer, Berlin, S 237–284
Fuhremann TW, Lichtenstein EP, Stratman FW (1978) Effects of naturally occurring food plant components on insecticide degradation in rats. J Agric Food Chem 26(5):1068–1075
Giusti GV, Moneta E (1973) A case of criminal abortion by ingestion of parsley decoction and naphthalene used vaginally. Arch Kriminol 152:161–164
Hartmann-Schreier J (2003) Apiol. In: Römpp – Lexikon der Chemie. https://roempp.thieme.de/roempp4.0/do/data/RD-01-02990. Zugegriffen: 22. Jan. 2019
Hausen BM (1997) Petroselinum crispum. In: Hausen BM, Vieluf I (Hrsg.) Allergiepflanzen-Pflanzenallergene. Ecomed, Landsberg a. Lech. S 200
Hermann K, Roux A, Fiddes FS (1956) Death from apiol used as abortifacient. The Lancet 267(6929):937–939
Koul O, Walia S, Dhaliwal GS (2008) Essential oils as green pesticides: potential and constraints. Biopestic Int 4(1):63–84
Krammer G (2004) Petersilienöle. In: Römpp – Lexikon der Chemie. https://roempp.thieme.de/roempp4.0/do/data/RD-16-01262. Zugegriffen: 24. Januar 2019
Krist S (2013) Petersiliensamenöl. In: Lexikon der pflanzlichen Fette und Öle. Springer, Wien, S 629–634
Mittelbach F (1984) Handekzem bei Kontaktallergie gegen Petersilie: Untersuchungen zur Allergenfindung und Kreuzallergie mit anderen Apiaceae (Umbelliferae). Aktuelle Dermatologie 10(2):52–55
Ochsmann J (2003) Some notes on problems of taxonomy and nomenclature of culti-vated plants. Schriften zu Genetischen Ressourcen, 42
Prentner A (2017) Heilpflanzen für Niere, Blase und Prostata. In: Heilpflanzen der Traditionellen Europäischen Medizin. Springer, Berlin, S 237–270
Stransky L, Tsankov N (1980) Contact dermatitis from parsley (Petroselinum). Contact Dermatitis 6(3):233–234
von Noorden C, Salomon H (1920) Handbuch der Ernährungslehre: Allgemeine Diätetik (Bd. 1). Springer. S 512–513
Weiss RF (1982) Lehrbuch der Phytotherapie. Hippokrates, Stuttgart. S 272
Literatur zu Abschn. 4.2.1.2.3
Koul O, Walia S, Dhaliwal GS (2008) Essential oils as green pesticides: potential and constraints. Biopestic Int 4(1), 63–84
Literatur zu Abschn. 4.2.1.2.4
BGBL (2001) Bundesgesetzblatt, Teil I Nr. 28, ausgegeben am 25.06.2001, Verordnung zur Änderung der Aromenverordnung und zur Aufhebung lebensmittelrechtlicher Vorschriften für Teigwaren vom 18.06.2001. S 1178
Chizzola R (2011) Composition of the essential oils from Anthriscus cerefolium var. trichocarpa and A. caucalis growing wild in the urban area of Vienna (Austria). Natural product communications 6(8):1147–1150
EG-Verordnung r. 1334/2008 des europäischen Parlamentes und des Rates vom 16. Dezember über Aromen und bestimmte Lebensmittelzutaten mit Aromaeigenschaften zur Verwendung in und auf Lebensmitteln sowie zur Änderung der Verordnung (EWG) Nr. 1601/91 des Rates, der Verordnungen (EG) Nr. 2232/96 und (EG) Nr. 110/2008 und der Richtlinie 2000/13/EG. Anhang III, Teil B. https://eur-lex.europa.eu/legal-content/DE/TXT/PDF/?uri=uriserv:OJ.L_.2008.354.01.0034.01.DEU. Zugegriffen: 26. Jan. 2019
Jenner PM, Hagan EC, Taylor JM, Cook EL, Fitzhugh OG (1964) Food flavourings and compounds of related structure I. Acute oral toxicity. Food Cosmet Toxicol 2:327–343
Krammer G (2006) Estragol. In: Eisenbrand G, Schreier P (Hrsg) Römpp – Lexikon der Lebensmittelchemie. Thieme, Stuttgart. S, S 321–322
Teuscher E (2010) Estragol. In: Teuscher E, Lindequist U (Hrsg) Biogene Gifte. Wissenschaftliche Verlagsgesellschaft, Stuttgart, S 324
Literatur zu Abschn. 4.2.1.2.5
Atsumi T, Tonosaki FS, K, (2005) A comparative study of the antioxidant/prooxidant activities of eugenol and isoeugenol with various concentrations and oxidation conditions. Toxicol In Vitro 19(8):1025–1033
Dammaschke T (2013) Einsatz biokompatibler Zemente bei der Vitalerhaltung der Pulpa und in der Endodontie. wissen kompakt 7(2):3–12
Epstein SS, Fujii K, Andrea J, Mantel N (1970) Carcinogenicity testing of selected food additives by parenteral administration to infant Swiss mice. Toxicol Appl Pharmacol 16(2):321–334
Iten F, Saller FI, Reichung J (2004) Naturstoffchemie – Sind Naturprodukte mit Methyleugenol kanzerogen? Deutsche Apotheker Zeitung (DAZ) 144(28):42–49. https://www.deutsche-apotheker-zeitung.de/daz-az/2004/daz-28-2004/uid-12255. Zugegriffen: 26. Jan. 2019
Johnson JD, Ryan MJ, Toft JD, Graves SW, Hejtmancik MR, Cunningham ML, Herbert R, Abdo KM (2000) Two-year toxicity and carcinogenicity study of methyleugenol in F344/N rats and B6C3F1 mice. J Agric Food Chem 48(8):3620–3632
Li YH, Sun ZH, Zheng P (2004) Determination of vanillin, eugenol and isoeugenol by RP-HPLC. Chromatographia 60(11–12):709–713
Marongiu B, Piras A, Porcedda S, Casu R, Pierucci P (2005) Comparative analysis of supercritical CO2 extract and oil of Pimenta dioica leaves. J Essent Oil Res 17(5):530–532
Mahrous HS, El-Far AH, Sadek KM, Abdel-Latif MA (2017) Effects of different levels of clove bud (syzygium aromaticum) dietary supplementation on immunity, antioxidant status, and performance in broiler chickens. Alexandria J Vet Sci 54(2)
Munerato MC, Sinigaglia M, Reguly ML, de Andrade HHR (2005) Genotoxic effects of eugenol, isoeugenol and safrole in the wing spot test of Drosophila melanogaster. Mutat Res/Genet Toxicol Environ Mutagen 582(1):87–94
Nacar S, Tansi S (2000) Chemical components of different basil (Ocimum basilicum L.) cultivars grown in Mediterranean regions in Turkey. Israel J Plant Sci 48(2):109–112
National Toxicology Program. (2010). Toxicology and carcinogenesis studies of isoeugenol (CAS No. 97-54-1) in F344/N rats and B6C3F1 mice (gavage studies). National Toxicology Program technical report series, (551), 1. https://www.ncbi.nlm.nih.gov/pubmed/21372857. Zugegriffen: 26. Jan. 2019
Prashar A, Locke IC, Evans CS (2006) Cytotoxicity of clove (Syzygium aromaticum) oil and its major components to human skin cells. Cell Prolif 39(4):241–248
Senanayake UM, Lee TH, Wills RB (1978) Volatile constituents of cinnamon (Cinnamomum zeylanicum) oils. J Agric Food Chem 26(4):822–824
Singh G, Marimuthu P, Heluani CSD, Catalan C (2005) Antimicrobial and antioxidant potentials of essential oil and acetone extract of Myristica fragrans Houtt.(aril part). J Food Sci 70(2):M141–M148
Sober HA, Hollander F, Sober EK (1950) Toxicity of Eugenol: Determination of LD50 on Rats. Proc Soc Exp Biol Med 73(1):148–151
Traboulsi AF, El-Haj S, Tueni M, Taoubi K, Nader NA, Mrad A (2005) Repellency and toxicity of aromatic plant extracts against the mosquito Culex pipiens molestus (Diptera: Culicidae). Pest Manag Sci: Formerly Pestic Sci 61(6):597–604
Uter W, Werfel T (2017) Aktuelles von der Kontaktallergie-Übersicht und Bewertung besonders interessanter Arbeiten aus 2016. Allergologie 40(6):227
Wagner H, Bladt S, Zgainski EM (1983) Ätherischöl-Drogen (Aetherolea). In Drogenanalyse. Springer, Berlin, S 5–49
WHO (2018) Methyleugenol. IARC-Monograph. https://monographs.iarc.fr/wp-content/uploads/2018/06/mono101-013.pdf. Zugegriffen: 26. Jan. 2019
Literatur zu Abschn. 4.2.1.2.6
Archer AW (1988) Determination of safrole and myristicin in nutmeg and mace by high-performance liquid chromatography. J Chromatogr A 438:117–121
Bowes KM, Zheljazkov VD, Caldwell CD, Pincock JA, Roberts JC (2004) Influence of seeding date and harvest stage on yields and essential oil composition of three cultivars of dill (Anethum graveolens L.) grown in Nova Scotia. Can J Plant Sci 84(4):1155–1160
Forrest JE, Heacock RA (1972) Nutmeg and mace, the psychotropic spices from Myristica fragrans. Lloydia 35(4):440–449
Forrest TP, Forrest JE, Heacock RA (1973) The isolation of some diarylpropanoids from nutmeg. Naturwissenschaften 60(5):257–258
Hattori M, Hada S, Shu YZ, Kakiuchi N, Namba T (1987) New acyclic bis-phenylpropanoids from the aril of Myristica fragrans. Chem Pharm Bull 35(2):668–674
Hattori M, Yang XW, Shu YZ, Kakiuchi N, Tezuka Y, Kikuchi T, Namba T (1988) New constituents of the aril of Myristica fragrans. Chem Pharm Bull 36(2):648–653
Hallström H, Thuvander A (1997) Toxicological evaluation of myristicin. Nat Toxins 5(5):186–192
Kalbhen DA (1971) Die Muskatnuß als Rauschdroge Ein Beitrag zur Chemie und Pharmakologie der Muskatnuß (Myristica fragrans). Angew Chem 83(11):392–396
Krist S (2013) Lexikon der pflanzlichen Fette und Öle. Springer-Verlag. S 503
Kovar KA (1981) Chemie und Wirkungsweise N-freier Halluzinogene. Pharm Unserer Zeit 10(3):65–74
Marcus C, Lichtenstein EP (1982) Interactions of naturally occurring food plant components with insecticides and pentobarbital in rats and mice. J Agric Food Chem 30(3):563–568
Menninger A (2001) Die Verbreitung von Schokolade, Kaffee, Tee und Tabak in Europa (16.–19. Jahrhundert). Ein Vergleich. Leimgruber, Yvonne, Fauz, Patrick, Rossfeld, Roman ua (Hrsg): Chocolat Tobler. Zur Geschichte der Schokolade und einer Berner Firma. Historisches Institut der Universität Bern, Bern, S 28–37
Prentner A (2010) Muskatnussbaum. In: Bewusstseinsverändernde Pflanzen von A–Z. Springer, Wien, S 201–208
Shulgin AT (1966) Possible implication of myristicin as a psychotropic substance. Nature 210(5034):380–384
Shulgin AT, Sargent T, Naranjo C (1967) The chemistry and psychopharmacology of nutmeg and of several related phenylisopropylamines. Psychopharmacol Bull 4(3)
Stein U, Greyer H, Hentschel H (2001) Nutmeg (myristicin) poisoning—report on a fatal case and a series of cases recorded by a poison information centre. Forensic Sci Int 118(1):87–90
Wink M, Van Wyk BE, Wink C (2008) Handbuch der giftigen und psychoaktiven Pflanzen. Wissenschaftliche Verlagsgesellschaft, Stuttgart
Literatur zu Abschn. 4.2.1.2.7
BGVV (2001) Gesundheitliche Bewertung von Duftölen, die Safrol, Methyleugenol oder Estragol enthalten. https://mobil.bfr.bund.de/cm/343/duftoele.pdf. Zugegriffen: 28. Jan. 2019
Chen SJ, Wu BN, Yeh JL, Lo YC, Chen IS, Chen IJ (1995) C-fiber-evoked autonomic cardiovascular effects after injection of Piper betle inflorescence extracts. J Ethnopharmacol 45(3):183–188
Clark AM (1976) Naturally occurring mutagens. Mutation Res/Rev Genet Toxicol 32(3–4):361–374
ECHA (2018) 5-allyl-1,3-benzodioxole –Substance Information – ECHA. https://echa.europa.eu/de/substance-information/-/substanceinfo/100.002.133. Zugegriffen: 29. Jan. 2019
Efferth T (2006) Molekulare Toxikologie. Molekulare Pharmakologie und Toxikologie: Biologische Grundlagen von Arzneimitteln und Giften, 153–259
Huang JK, Huang CJ, Chen WC, Liu SI, Hsu SS, Chang HT, Tseng LL, Chou CT, Chang CH, Jan CR (2005) Independent [Ca 2+] i increases and cell proliferation induced by the carcinogen safrole in human oral cancer cells. Naunyn-Schmiedeberg’s Arch Pharmacol 372(1):88–94
Jenner PM, Hagan EC, Taylor JM, Cook EL, Fitzhugh OG (1964) Food flavourings and compounds of related structure I. Acute oral toxicity. Food Cosmet Toxicol 2:327–343
Kamdem DP, Gage DA (1995) Chemical composition of essential oil from the root bark of Sassafras albidum. Planta Med 61(06):574–575
Lee JM, Liu TY, Wu DC, Tang HC, Leh J, Wu MT, Hsu HH, Huang PM, Chen JS, Lee CJ, Lee YC (2005) Safrole–DNA adducts in tissues from esophageal cancer patients: clues to areca-related esophageal carcinogenesis. Mutat Res/Genet Toxicol Environ Mutagen 565(2):121–128
Przyrembel H (2003) Arzneipflanzen in Nahrungsergänzungsmitteln. Bundesgesundheitsblatt-Gesundheitsforschung-Gesundheitsschutz 46(12):1074–1079
Surburg H, Panten J (2016) Common fragrance and flavor materials: preparation, properties and uses. Wiley
Wu MT, Lee YC, Chen CJ, Yang PW, Lee CJ, Wu DC, Hsu HK, Ho CK, Kao EL, Lee JM (2001) Risk of betel chewing for oesophageal cancer in Taiwan. Br J Cancer 85(5):658
Zhang GF, Chen CJ (2006) Analysis on chemical components and their contents of essential oil from Cinnamomum camphora leaf in Fujian Province. J Plant Res Environ 15(4):69
Literatur zu Abschn. 4.2.1.2.8
Banovac D (2012) Antimikrobielle Wirkung ausgewählter flüchtiger Verbindungen und ätherischer Öle auf luftgetragene Keime. Diplomarbeit, Universität Wien. Fakultät für Lebenswissenschaften BetreuerIn: Krist, Sabine. URN: urn:nbn:at:at-ubw:1–29635.47749.763169-0. Zugegriffen: 29. Jan. 20129
Brodie JF (2001) Menstrual interventions in the nineteenth-century United States. Regulating menstruation: Beliefs, practices, interpretations, 39
EG-Verordnung (2008) Nr.1334/2008 des europäischen Parlamentes und des Rates über Aromen und bestimmte Lebensmittelzutaten mit Aromaeigenschaften zur Verwendung in und auf Lebensmitteln sowie zur Änderung der Verordnung (EWG) Nr. 1601/91 des Rates, der Verordnungen (EG) Nr. 2232/96 und (EG) Nr. 110/2008 und der Richtlinie 2000/13/EG. https://eur-lex.europa.eu/legal-content/DE/TXT/?uri=CELEX:32008R1334. Zugegriffen: 29. Jan. 2019
Hausen BM (1997) Cinnamomum zeylanicum. In: Hausen BM, Vieluf I (Hrsg.) Allergiepflanzen-Pflanzenallergene. ecomed, Landsberg a. Lech. S 97–99
Jenner PM, Hagan EC, Taylor JM, Cook EL, Fitzhugh OG (1964) Food flavourings and compounds of related structure I. Acute oral toxicity. Food Cosmet Toxicol 2:327–343
Kim JR, Jeong IH, Lee YS, Lee SG (2015) Insecticidal activity of cinnamon essential oils, constituents, and (E)-cinnamaldehyde analogues against Metcalfa pruinosa Say (Hemiptera: Flatidae) nymphs and adults. Korean J Appl Entomol 54(4):375–382
Khan A, Safdar M, Khan MMA, Khattak KN, Anderson RA (2003) Cinnamon improves glucose and lipids of people with type 2 diabetes. Diabetes Care 26(12):3215–3218
Kitagawa H, Iwaki R (1963) Coumarin derivatives for medicinal purposes. XVII. Pharmacological studies on coumarin derivatives having biological activity. Yakugaku zasshi: J Pharm Soc Japan 83:1124
Madan KD (1998) Life and travels of Vasco da Gama. Asian Educational Services
Mang B, Wolters M, Schmitt B, Kelb K, Lichtinghagen R, Stichtenoth DO, Hahn A (2006) Effects of a cinnamon extract on plasma glucose, HbA1c, and serum lipids in diabetes mellitus type 2. Eur J Clin Invest 36(5):340–344
Miranda F, Brandão F, Silvad R (1990) Cosmetic contact dermatitis (1984–1989). Contact Dermatitis 23(4):242–243
Samarasekera R, Kalhari KS, Weerasinghe IS (2006) Insecticidal activity of essential oils of Ceylon Cinnamomum and Cymbopogon species against Musca domestica. J Essent Oil Res 18(3):352–354
Schnuch A, Griem P (2018) Duftstoffe als Allergene. Allergo J 27(6):42–54
Schormüller J (2013) Alkaloidhaltige Genussmittel, Gewürze, Kochsalz (Bd 6). Springer
Siedentopp U (2008) Heilpflanze Chinesischer Zimt. Dtsch Z Akupunktur 51(4):62–65
Simoons FJ (2014) Food in China: a cultural and historical inquiry. CRC Press
Wang YH, Avula B, Nanayakkara ND, Zhao J, Khan IA (2013) Cassia cinnamon as a source of coumarin in cinnamon-flavored food and food supplements in the United States. J Agric Food Chem 61(18):4470–4476
Literatur zu Abschn. 4.2.2
Andersen HH, Møller G, Winter R, Eskelund P, Arendt-Nielsen L (Aug 2013) A review of topical high-concentration L-menthol as a translational model of cold allodynia and hyperalgesia. Eur J Pain 18(3):315–325. https://doi.org/10.1002/j.1532-2149.2013.00380.x.PMID23963768
Caterina MJ, Schumacher MA, Tominaga M, Rosen TA (1997) The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 389(6653):816–824
Hensel H (1981) Thermoreception and temperature regulation. Monogr Physiol Soc 38:1–321
Macpherson LJ, Geierstanger BH, Viswanath V, Bandell M, Eid SR, Hwang S, Patapoutian A (2005) The pungency of garlic: activation of TRPA1 and TRPV1 in response to allicin. Curr Biol 15(10):929–934
McNamara FN, Randall A, Gunthorpe MJ (2005) Effects of piperine, the pungent component of black pepper, at the human vanilloid receptor (TRPV1). Br J Pharmacol 144(6):781–790
Rein H (1925a) Beiträge zu der Lehre von der Temperaturempfindung der menschlichen Haut. Z BioI 82:189–212
Rein H (1925b) Über die Topographie der Warmempfindung. Beziehungen zwischen Innervation und receptorischen Endorganen. Z BioI 82:513–535
Strughold H, Porz R (1931) Die Dichte der Kaltpunkte auf der Haut des menschlichen Körpers. Z BioI 91:563–571
Wiesenauer M (2012) Scharfstoffe. In: PhytoPraxis. Berlin, Heidelberg, S 222
Xu H, Blair NT, Clapham DE (2005) Camphor activates and strongly desensitizes the transient receptor potential vanilloid subtype 1 channel in a vanilloid-independent mechanism. J Neurosci 25(39):8924–8937
Zygmunt PM, Peterson J, Andersson DA, Chuang H, Sørgård M, Di Marzo V, Julius D, Högestätt ED (1999) Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide. Nature 400(6743):452–457
Literatur zu Abschn. 4.2.2.1.1
Daunderer M (1990) Drogenhandbuch für Klinik und Praxis: Diagnose, Nachweis, Therapie, Prophylaxe, Recht, Drogenprofile. Ecomed
Flaman Z, Pellechia S, Bailey B, McGuigan M (2001) Unintentional exposure of young children to camphor and eucalyptus oils. Paediatrics & child health 6(2):80–83
Hänsel R (1972) Ätherische Öle, Harze, Balsame. In: Steinegger E, Hänsel R (Hrsg) Lehrbuch der Pharmakognosie: auf phytochemischer Grundlage. Springer, S 421
Hänsel R, Hölzl J (1996) Ätherische Öle, Campher. I: Hänsel R, Hölzl J (Hrsg) Lehrbuch der pharmazeutischen Biologie. Springer, Berlin, S 149–151
Hempel B (2000) Toxikologie von D-Campher. In Phytopharmaka VI (S 29–37). Steinkopff, Heidelberg
Hänsel R (1994) Kampfer. In: Hänsel R, Keller K, Rimpler H, Schneider G (Hrsg.BB) Hagers Handbuch der pharmazeutischen Praxis. Band 6, Drogen P–Z, S 496–500, 551–557, ISBN 3-540-52639-0
Koll W, Haase J, Schütz RM, Mühlberg B (1961) Reflexentladungen der tiefspinalen Katze durch afferente Impulse aus hochschwelligen nociceptiven A-Fasern (post δ-Fasern) und aus nociceptiven C-Fasern cutaner Nerven. Pflüger’s Arch Gesamte Physiol Menschen Tiere 272(3):270–289
Geller RJ, Spyker DA, Garrettson LK, Rogol AD (1984) Camphor toxicity: development of a triage strategy. Vet Hum Toxicol 26:8–10
Gouin S, Patel H (1996) Unusual cause of seizure. Pediatr Emerg Care 12(4):298–300
Kopke K (2010) Die Atemstimulierende Einreibung (ASE)-Eine pflegerische Interventionsstudie zur Schmerzreduktion bei mehrfach erkrankten älteren Menschen (Doctoral dissertation, Medizinische Fakultät Charité-Universitätsmedizin Berlin)
Kroll M, Ring C, Gaus W, Hempel B (2005) A randomized trial of Korodin® Herz-Kreislauf-Tropfen as add-on treatment in older patients with orthostatic hypotension. Phytomedicine 12(6–7):395–402
Love JN, Sammon M, Smereck J (2004) Are one or two dangerous? camphor exposure in toddlers. J Emerg Med 27(1):49–54
Lübke G (2003) Ätherische Öle. In: v. Mühlendahl KE, Oberdisse U, Bunjes R, Brockstedt M (Hrsg) Vergiftungen im Kindesalter. Thieme, Stuttgart, S 68–70
Opdyke DLJ (1978) Camphor USP. Monographs on fragrance materials. Food Cosmet Toxicol 16(1):665–671
Pandey AK, Bora HR, Deka SC, Rastogi RC, Baruah AKS (1997) Composition of the essential oil of the bark of Cinnamomum camphora. J Med Aromat Plant Sci 19(2):408–409
Poppenga RH (2002) Herbal medicine: potential for intoxication and interactions with conventional drugs. Clin Tech Small Anim Pract 17(1):6–18
Prentner A (2017) Heilpflanzen für Gelenke, Knochen und Schmerzen. In Heilpflanzen der Traditionellen Europäischen Medizin (S. 397–423). Springer, Berlin
Richter A, Löscher W 2006) Phytotherapeutika. In: Löscher W, Ungemach FR, Kroker R (Hrsg) Pharmakotherapie bei Haus-und Nutztieren. Georg Thieme
Schlumpf M, Kypke K, Vökt CC, Birchler M, Durrer S, Faass O, Ehnes C, Fuetsch M, Gaille C, Henseler M, Hofkamp L Maerkel K, Reolon S, Zenker A, Timms BB, Tresguerres JAF, Lichtsteigera W (2008) Endocrine active UV filters: developmental toxicity and exposure through breast milk. CHIMIA Int J Chem 62(5):345–351
Selescu T, Ciobanu AC, Dobre C, Reid G, Babes A (2013) Camphor activates and sensitizes transient receptor potential melastatin 8 (TRPM8) to cooling and icilin. Chem Senses 38(7):563–575
Ständer S, Zeidler C, Augustin M, Bayer G, Kremer AE, Legat FJ, Maisel, P, Mettang Th, Metz M, Nast A, Niemeier V, Raap U, Schneider G, Ständer HF, Staubach P, Streit M, Weishaar E (2017) S2k‐Leitlinie zur Diagnostik und Therapie des chronischen Pruritus–Update–Kurzversion. JDDG: J Dtsch Dermatologischen Ges 15(8):860–873
Stahl PH, Wermuth, CG (2002) Monographs on acids and bases. Handbook of Pharmaceutical Salts: Properties, Selection, and Use, 265–266
Strughold H, Porz, R (1931) Die Dichte der Kaltpunkte auf der Haut des menschlichen Körpers. Z BioI 91:563-571
Weiss J, Catalano P (1973) Camphorated oil intoxication during pregnancy. Pediatrics 52(5):713–714
Wiesenauer M (2012) Scharfstoffe. In: PhytoPraxis, Berlin, Heidelberg, S 222
Literatur zu Abschn. 4.2.2.1.1.2
Bacon FJ (1928) The botanical origin of American peppermint—Mentha piperita L. Journal of the American Pharmaceutical Association, 17(11):1094–1096
Bautista DM, Siemens J, Glazer JM, Tsuruda PR, Basbaum AI, Stucky CL, Jordt SE, Julius D (2007) The menthol receptor TRPM8 is the principal detector of environmental cold. Nature 448(7150):204
EU-Richtlinie 2014/40 (2014) Richtlinie des Europäischen Parlaments und des Rates vom 3. April 2014 zur Angleichung der Rechts-und Verwaltungsvorschriften der Mitgliedstaaten über die Herstellung, die Aufmachung und den Verkauf von Tabakerzeugnissen und verwandten Erzeugnissen und zur Aufhebung der Richtlinie 2001/37/EG. EG-Text von Bedeutung für den EWR
Hänsel R, Hölzl J (1996) Ätherische Öle. In: Hänsel R, Hölzl J (Hrsg) Lehrbuch der pharmazeutischen Biologie. Springer, S 128–132
Hensel H, Zottermann Y (1951) The effect of menthol on the thermoreceptors. Acta Physiol Physiologica Scandinavica 24(1):27–34
Krammer G, Menzel M (2008a) Menthol. In: Römpp-Online – Lexikon der Chemie. Thieme, Stuttgart. https://roempp.thieme.de/roempp4.0/do/data/RD-13-01237
Krammer G, Menzel M (2008b) Pfefferminzöle. In: Römpp-Online – Lexikon der Chemie. Thieme, Stuttgart. https://roempp.thieme.de/roempp4.0/do/data/RD-16-01328
Paschke M, Tkachenko A, Ackermann K, Hutzler C, Henkler F, Luch A (2017) Activation of the cold-receptor TRPM8 by low levels of menthol in tobacco products. Toxicol letters 271:50–57
Plevkova J, Kollarik M, Poliacek I, Brozmanova M, Surdenikova L, Tatar M, Mori N, Canning BJ (2013) The role of trigeminal nasal TRPM8-expressing afferent neurons in the antitussive effects of menthol. Journal of Applied Physiology 115(2):268–274
Schäfer B (2013) Menthol: Minze versus Tagasako-Prozess. Chemie unserer Zeit 47(3):174–182
Wei ET, Seid DA (1983) AG-3–5: a chemical producing sensations of cold. Journal of Pharmacy and Pharmacology 35(2):110–112
Wickham RJ (2015) Focus: Addiction: How Menthol Alters Tobacco-Smoking Behavior: A Biological Perspective. The Yale journal of biology and medicine 88(3):279
Literatur zu Abschn. 4.2.2.1.2
Atsumi T, Fujisawa S. Tonosaki K (2005) A comparative study of the antioxidant/prooxidant activities of eugenol and isoeugenol with various concentrations and oxidation conditions. Toxicology in vitro 19(8):1025–1033
Dammaschke T (2013) Einsatz biokompatibler Zemente bei der Vitalerhaltung der Pulpa und in der Endodontie. wissen kompakt 7(2):3–12
Epstein, SS, Fujii K, Andrea J, Mantel N (1970) Carcinogenicity testing of selected food additives by parenteral administration to infant Swiss mice. Toxicol Appl Pharmacol 16(2):321–334
Iten F, Saller FI, Reichung J (2004) Naturstoffchemie – Sind Naturprodukte mit Methyleugenol kanzerogen? Deutsche Apotheker Zeitung (DAZ) 144(28):42–49. https://www.deutsche-apotheker-zeitung.de/daz-az/2004/daz-28-2004/uid-12255. Zugegriffen: 26. Jan. 2019
Johnson JD, Ryan MJ, Toft JD, Graves SW, Hejtmancik MR, Cunningham ML, Herbert R, Abdo KM (2000) Two-year toxicity and carcinogenicity study of methyleugenol in F344/N rats and B6C3F1 mice. J Agric Food Chem 48(8):3620–3632
Krist S (2013) Lexikon der pflanzlichen Fette und Öle. Springer, S 503
Li YH, Sun ZH, Zheng P (2004) Determination of vanillin, eugenol and isoeugenol by RP-HPLC. Chromatographia 60(11–12):709–713
Marongiu B, Piras A, Porcedda S, Casu R, Pierucci P (2005) Comparative analysis of supercritical CO2 extract and oil of Pimenta dioica leaves. J Essen Oil Res 17(5):530–532
Mahrous HS, El-Far AH, Sadek KM, Abdel-Latif MA (2017) Effects of Different Levels of Clove Bud (Syzygium Aromaticum) Dietary Supplementation on Immunity, Antioxidant Status, and Performance in Broiler Chickens. Alexandria J Vet Sci 54(2)
Munerato MC, Sinigaglia M, Reguly ML, de Andrade HHR (2005) Genotoxic effects of eugenol, isoeugenol and safrole in the wing spot test of Drosophila melanogaster. Mutat Res/Genet Toxicol Environ Mutagen 582(1):87–94
Nacar S, Tansi S (2000) Chemical components of different basil (Ocimum basilicum L.) cultivars grown in Mediterranean regions in Turkey. Isr J Plant Sci 48(2):109–112
National Toxicology Program (2010) Toxicology and carcinogenesis studies of isoeugenol (CAS No. 97-54-1) in F344/N rats and B6C3F1 mice (gavage studies). National Toxicology Program technical report series, (551), 1. https://www.ncbi.nlm.nih.gov/pubmed/21372857. Zugegriffen: 26. Jan. 2019
Prashar A, Locke IC, Evans CS (2006) Cytotoxicity of clove (Syzygium aromaticum) oil and its major components to human skin cells. Cell Prolif 39(4):241–248
Prashar A, Locke IC, Evans CS (2006) Cytotoxicity of clove (Syzygium aromaticum) oil and its major components to human skin cells. Cell Prolif 39(4):241–248
Schaaf F, Gross F (1953) Tierexperimentelle Untersuchungen mit Salben und Salbengrundlagen. Dermatology 106(6):357–378
Sexton JE, Vernon J, Wood JN (2014) TRPs and pain. In: Mammalian Transient Receptor Potential (TRP) Cation Channels. Springer, Cham, S 873–897
Sober HA, Hollander F, Sober EK (1950) Toxicity of Eugenol: Determination of LD50 on Rats. Proc Soc Exp Biol Med 73(1):148–151
Traboulsi AF, El‐Haj S, Tueni M, Taoubi K, Nader NA, Mrad A (2005) Repellency and toxicity of aromatic plant extracts against the mosquito Culex pipiens molestus (Diptera: Culicidae). Pest Manage Sci: Formerly Pestic Sci 61(6):597–604
Uter W, Werfel T (2017) Aktuelles von der Kontaktallergie-Übersicht und Bewertung besonders interessanter Arbeiten aus 2016. Allergologie 40(6):227
Wagner H, Bladt S, Zgainski EM (1983) Ätherischöl-Drogen (Aetherolea). In Drogenanalyse. Springer, Berlin, S 5–49
WHO (2018) Methyleugenol. IARC-Monograph. https://monographs.iarc.fr/wp-content/uploads/2018/06/mono101-013.pdf. Zugegriffen: 26. Jan. 2019
Literatur zu Abschn. 4.2.2.1.3
Asero R, Mistrello G, Roncarolo D, Antoniottib PL, Falagiani P (1998) A case of garlic allergy. J Allergy Clin Immunol 101(3):427–428
Avato P, Tursi F, Vitali C, Miccolis V, Candido V (2000) Allylsulfide constituents of garlic volatile oil as antimicrobial agents. Phytomedicine 7(3):239–243
Bassioukas K, Orton D, Cerio R (2004) Occupational airborne allergic contact dermatitis from garlic with concurrent Type I allergy. Contact Dermatitis 50(1):39–41
Beaumont P, Moneret-Vautrin DA, Dzviga C, Grand JL (2013) Anaphylaxie alimentaire à l’oignon et à l’ail: insuffisance des prick-tests et des IgE spécifiques à la source allergénique. À propos de cinq cas. Revue Française d'Allergologie 53(5):446–449
Block E (1992) Die Organoschwefelchemie der Gattung Allium und ihre Bedeutung für die organische Chemie des Schwefels. Angew Chem 104:1158–1203. https://doi.org/10.1002/ange.19921040906
Block E (2010) Garlic and other alliums: The lore and the science. Royal society of chemistry. Verlag RSC, Cambridge, S 152–166
Casetti F, Huber R, Schempp CM (2011) Unverträglichkeitsreaktionen der Haut auf Pflanzen. Schweiz Z Ganzheitsmedizin/Swiss J Integr Med 23(3):144–146
Chan EF, Mowad C (1998) Contact dermatitis to foods and spices. Am J Contact Dermatitis 9(2):71–79
Chase MW, Reveal JL, Fay MF (2009) A subfamilial classification for the expanded asparagalean families Amaryllidaceae, Asparagaceae and Xanthorrhoeaceae. Bot J Linn Soc 161(2):132–136
Habermehl GG, Ziemer P (1999) Mitteleuropäische Giftpflanzen und ihre Wirkstoffe. Springer, Berlin
Hänsel R (2013) Pflanzliche Lipidsenker. Arzneidrogen in der Medizin heute. In: Dingermann T, Hänsel R, Zündorf I (Hrsg) Pharmazeutische Biologie: Molekulare Grundlagen und klinische Anwendung. Springer, S 61
Hjorth N, Roed J (1976) Occupational protein contact dermatitis in food handlers. Contact Dermatitis 2(1):28–42
Jappe U, Bonnekoh B, Hausen BM, Gollnick H (1999) Garlic-related dermatoses: case report and review of the literature. Am J Contact Dermatitis 10(1):37–39
Krammer G (2004) Propanthialoxid. In: Römpp – Lexikon der Chemie. Thieme, Stuttgart. https://roempp.thieme.de/roempp4.0/do/data/RD-16-04331. Zugegriffen: 12. Febr. 2019
Lee TY, Lam TH (1991) Contact dermatitis due to topical treatment with garlic in Hong Kong. Contact Dermatitis 24(3):193–196
Legrum W (2011) Riechstoffe, Zwischen Gestank und Duft: Vorkommen, Eigenschaften und Anwendung von Riechstoffen und deren Gemischen. Springer
Mitchell JC (1980) Contact sensitivity to garlic (Allium). Contact Dermatitis 6(5):356–357
Negishi O, Negishi Y, Ozawa T (2002) Effects of food materials on removal of allium-specific volatile sulfur compounds. J Agric Food Chem 50(13):3856–3861
Rae HA (1999) Onion toxicosis in a herd of beef cows. Can Vet J 40(1):55
Rao RR, Natarajan S (1949) Toxicity of pterygospermin and allicin. Proc: Plant Sci 29(4):148–154
Rimbach G, Nagursky J, Erbersdobler HF (2015) Gewürze. In: Lebensmittel-Warenkunde für Einsteiger. Springer Spektrum, Berlin, 261–282
Schempp CM, Schöpf E, Simon JC (2002) Durch Pflanzen ausgelöste toxische und allergische Dermatitis (Phytodermatitis). Der Hautarzt 53(2):93–97
Teuscher E (1979) Lauchöle. In: Pharmazeutische Biologie. Vieweg, Braunschweig, S 422–424
Literatur zu Abschn. 4.2.2.1.4
Alpizar YA, Boonen B, Gees M, Sanchez A, Nilius B, Voets T, Talavera K (2014)
Allyl isothiocyanate sensitizes TRPV1 to heat stimulation. Pflügers Arch-Eur J Physiol 466(3):507–515
Bäumler S (2012) Senf. In: Heilpflanzen Praxis heute. Bd 1: Heilpflanzenportraits. Elsevier, München, S 560–562
Hanschen FS, Lamy E, Schreiner M, Rohn S (2014) Reactivity and stability of glucosinolates and their breakdown products in foods. Angew Chem Int Ed 53(43):11430–11450
Herzallah S, Holley R (2012) Determination of sinigrin, sinalbin, allyl-and benzyl isothiocyanates by RP-HPLC in mustard powder extracts. LWT-Food Sci Technol 47(2):293–299
Leitzmann C (2010) Sekundäre Pflanzenstoffe in Lebensmitteln. In: Ernährung und Fasten als Therapie. Springer, Berlin, S 49–59
Teuscher E (2010) Glukosinolate. In: Teuscher E, Lindequist U (Hrsg) Biogene Gifte. Wissenschaftliche Verlagsgesellschaft, Stuttgart, S 452
Literatur zu Abschn. 4.2.2.2.1
Ali MA, Alam NM, Yeasmin MS, Khan AM, Sayeed MA, Rao VB (2007) Antimicrobial screening of different extracts of Piper longum Linn. Res J Agri Biol Sci 3(6):852–857
Cardoso VS, Castro IS, Lima CAR, Lima MEF, Dorneles LEG, Direito GM, Danelli MGM (2011) Efficacy of piperine in reducing the effects of aflatoxin intoxication in broiler chickens: a preliminary report. Arq Bras Med Vet e Zootecnia 63(2):495–498
Francis LP, Francis GW (1977) Sedum alkaloids. Planta Med 32(07):268–274
Freedman P (2005) Spices and late-medieval European ideas of scarcity and value. Speculum 80(4):1209–1227
Geng S, Zheng Y, Meng M, Guo Z, Cao N, Ma X, Du Z, Li J, Duan Y, Du G (2016) Gingerol reverses the cancer-promoting effect of capsaicin by increased TRPV1 level in a urethane-induced lung carcinogenic model. J Agric Food Chem 64(31):6203–6211
Gough TA, Goodhead K (1975) Occurrence of volatile nitrosamines in spice premixes. J Sci Food Agric 26(10):1473–1478
Jirovetz L, Buchbauer G, Ngassoum MB, Geissler M (2002) Aroma compound analysis of Piper nigrum and Piper guineense essential oils from Cameroon using solid-phase microextraction–gas chromatography, solid-phase microextraction–gas chromatography–mass spectrometry and olfactometry. J Chromatogr A 976(1–2):265–275
Kapoor IPS, Singh B, Singh G, De Heluani CS, De Lampasona MP, Catalan CA (2009) Chemistry and in vitro antioxidant activity of volatile oil and oleoresins of black pepper (Piper nigrum). J Agric Food Chem 57(12):5358–5364
Kolesnikov DG, Shvartsman AG (1939) Alkaloids of Sedum acre L. Zh Obshch Khim 9:2156
Manrique V, Cuda JP, Overholt WA (2013) Brazilian peppertree: a poster child for invasive plants in Florida. J Florida Stud 1:1–14
Marion L (1945) The alkaloids of sedum acre L. Can J Res 23(5):165–166
McNamara FN, Randall A, Gunthorpe MJ (2005) Effects of piperine, the pungent component of black pepper, at the human vanilloid receptor (TRPV1). Br J Pharmacol 144(6):781–790
Perez Gutierrez RM, Neira AM, Hoyo-Vadillo C (2013) Alkaloids from piper: a review of its phytochemistry and pharmacology. Mini Rev Med Chem 13(2):163–193
Piyachaturawat P, Glinsukon T, Toskulkao C (1983) Acute and subacute toxicity of piperine in mice, rats and hamsters. Toxicol Lett 16(3–4):351–359
Rose JE, Behm FM (1994) Inhalation of vapor from black pepper extract reduces smoking withdrawal symptoms. Drug Alcohol Depend 34(3):225–229
Sharma PK, Pandey H, Dubey P, Jain M, Bhargav D (2012) Physico-chemical characterization and identification of alkaloids from piper nigrum (Piperaceae). Int J Pharm Res Dev (IJPRD) 4(08):5–10
Siedentopp U (2008) Heilpflanze Ingwer—wirksam als Arznei, Gewürz und Tee. Dtsch Z Akupunktur 51(1):72–75
Sterner O, Steffan B, Steglich W (1987) Novel azepine derivatives from the pungent mushroomchalciporus piperatus. Tetrahedron 43(6):1075–1082
Sudjarwo SA, Eraiko K, Giftania K (2017) Protective effects of piperine on lead acetate induced-nephrotoxicity in rats. Iran J Basic Med Sci 20(11):1227
Turner J (2005) Spice: the history of a temptation. Vintage Books/Random House, New York
Wood M, Steven F, Boom M (1998) The Boletes of California (online edition) ehemals: Thiers HD (1975) California Mushrooms – A Field Guide to the Boletes. Hafner Press, New York
Yaffe PB, Doucette CD, Walsh M, Hoskin DW (2013) Piperine impairs cell cycle progression and causes reactive oxygen species-dependent apoptosis in rectal cancer cells. Exp Mol Pathol 94(1):109–114
Backonja M, Wallace MS, Blonsky ER, Cutler BJ, Malan Jr P, Rauck R, Tobias J and the NGX-4010 C116 Study Group (2008) NGX-4010, a high-concentration capsaicin patch, for the treatment of postherpetic neuralgia: a randomised, double-blind study. Lancet Neurol 7(12):1106–1112
Barbero GF, Ruiz AG, Liazid A, Palma M, Vera JC, Barroso CG (2014) Evolution of total and individual capsaicinoids in peppers during ripening of the Cayenne pepper plant (Capsicum annuum L.). Food Chem 153:200–206
Barboza GE, Agra MF, Romero MV, Scaldaferro MA, Moscone EA (2011) New endemic species of Capsicum (Solanaceae) from the Brazilian Caatinga: comparison with the re-circumscribed C. parvifolium. Syst Bot 36(3):768–781
Barboza GE (2011) Lectotypifications, synonymy, and a new name in Capsicum (Solanoideae, Solanaceae). PhytoKeys 2:23
Becker H (1981) Scharfstoffe. Pharm Unserer Zeit 10(3):75–80
Cisneros-Pineda O, Torres-Tapia LW, Gutiérrez-Pacheco LC, Contreras-Martín F, González-Estrada T, Peraza-Sánchez SR (2007) Capsaicinoids quantification in chili peppers cultivated in the state of Yucatan, Mexico. Food Chem 104:1755–1760
EG-Verordnung Nr.1334 (2008) Verordnung (EG) Nr. 1334/2008 des Europäischen Parlamentes und des Rates vom 16. Dezember 2008 über Aromen und bestimmte Lebensmittelzutaten mit Aromaeigenschaften zur Verwendung in und auf Lebensmitteln sowie zur Änderung der Verordnung (EWG) Nr. 1601/91 des Rates, der Verordnungen (EG) Nr. 2232/96 und (EG) Nr. 110/2008 und der Richtlinie 2000/13/EG, Anhang III, Teil A. L 354/47. https://eur-lex.europa.eu/legal-content/DE/TXT/PDF/?uri=uriserv:OJ.L_.2008.354.01.0034.01.DEU. Zugegriffen: 8. Okt. 2019
Fett DD (2003) Botanical briefs: Capsicum peppers. Cutis 72(1):21–23
González-Zamora A, Sierra-Campos E, Luna-Ortega J, Pérez-Morales R, Ortiz J, García-Hernández J (2013) Characterization of different capsicum varieties by evaluation of their capsaicinoids content by high performance liquid chromatography, determination of pungency and effect of high temperature. Molecules 18(11):13471–13486
Hänsel R, Hölzl J (1996) Cayennepfeffer. In Lehrbuch der pharmazeutischen Biologie. Berlin, Heidelberg, S 257–259
Kennedy WR, Vanhove GF, Lu SP, Tobias J, Bley KR, Walk D, Wendelschafer-Crabb G, Simone DA, Selim, MM (2010) A randomized, controlled, open-label study of the long-term effects of NGX-4010, a high-concentration capsaicin patch, on epidermal nerve fiber density and sensory function in healthy volunteers. J Pain 11(6):579–587
Kozukue N, Han JS, Kozukue E, Lee SJ, Kim JA, Lee KR, Levein CE, Friedman M (2005) Analysis of eight capsaicinoids in peppers and pepper-containing foods by high- performance liquid chromatography and liquid chromatography-mass spectrometry. J Agric Food Chem 53:9172–9181
LaMotte RH, Shain CN, Simone DA, Tsai EF (1991) Neurogenic hyperalgesia: psychophysical studies of underlying mechanisms. Journal of neurophysiology 66(1):190–211
Lindequist U (2010) Amine. In: Teuscher E, Lindequist U (Hrsg.) Biogene Gifte. Wissenschaftliche Verlagsgesellschaft, Stuttgart, 415–417
Maggi CA, Meli A (1988) The sensory-efferent function of capsaicin-sensitive sensory neurons. Gen Pharmacol 19:1–43
Mason L, Moore RA, Derry S, Edwards JE, McQuay HJ (2004) Systematic review of topical capsaicin for the treatment of chronic pain. Brit Med J 328(7446):991
Moscone EA, Scaldaferro MA, Grabiele M, Cecchini NM, Sánchez García Y, Jarret R, Daviñia RA, Ducasse DA, Barboza GE, Ehrendorfer F (2006) The evolution of chili peppers (Capsicum-Solanaceae): a cytogenetic perspective. In VI International Solanaceae Conference: Genomics Meets Biodiversity 745, S 137–170
Nolano M, Simone DA, Wendelschafer-Crabb G, Johnson T, Hazen E, Kennedy WR (1999) Topical capsaicin in humans: parallel loss of epidermal nerve fibers and pain sensation. Pain 81(1–2):135–145
O'Neill J, Brock C, Olesen AE, Andresen T, Nilsson M, Dickenson AH (2012) Unravelling the mystery of capsaicin: a tool to understand and treat pain. Pharmacol Rev 64(4):939–971
Othman ZAA, Ahmed YBH, Habila MA, Ghafar AA (2011) Determination of capsaicin and dihydrocapsaicin in Capsicum fruit samples using high performance liquid chromatography. Molecules 16(10):8919–8929
Reimann S, Luger T, Metze D (2000) Topische Anwendung von Capsaicin in der Dermatologie zur Therapie von Juckreiz und Schmerz. Hautarzt 51(3):164–172
Saito A, Yamamoto M (1996) Acute oral toxicity of capsaicin in mice and rats. J Toxicol Sci 21(3):195–200
Schubert G (2015) Wem gehört der/die/das Paprika? Culinaria balcanica 24:55
Schubert-Sollberg E, Sollberg S (1998) Pruritus – Ursachen und Behandlungsmöglichkeiten. MMP 8:230–235
Schulzeck S, Wulf H (1997) Lokaltherapie mit Capsaicin oder ASS bei chronischen Schmerzen. Der Schmerz 11(5):345–352
Scoville, Wilbur (May 1912) Note on capsicums. J Am Pharm Assoc 1(5):453–454
Simone DA, Nolano M, Johnson T, Wendelschafer-Crabb G, Kennedy WR (1998) Intradermal injection of capsaicin in humans produces degeneration and subsequent reinnervation of epidermal nerve fibers: correlation with sensory function. J Neurosci 18(21):8947–8959
Staender S, Luger T, Metze D (2001) Treatment of prurigo nodularis with topical capsaicin. J Am Acad Dermatol 44(3):471–478
Thapa B, Skalko-Basnet N, Takano A, Masuda K, Basnet P (2009). High-performance liquid chromatography analysis of capsaicin content in 16 capsicum fruits from Nepal. J Med Food 12:908–913
Thomas BV, Schreiber AA, Weisskopf CP (1998) Simple method for quantitation of capsaicinoids in peppers using capillary gas chromatography. J Agric Food Chem 46:2655–2663
Touska F, Marsakova L, Teisinger J, Vlachova V (2011) A “cute” desensitization of TRPV1. Curr Pharm Biotechnol 12(1):122–129
Wiesenauer M (2012) Scharfstoffe. In: PhytoPraxis. Berlin, Heidelberg, S 222
Yang CY, Mandal PK, Han KH, Fukushima M, Choi K, Kim CJ, Lee CH (2010) Capsaicin and tocopherol in red pepper seed oil enhances the thermal oxidative stability during frying. J Food Sci Technol 47(2):162–165
Zatyko L (2006) Selection of paprika in ancient times and today. Acta Agronomica Hungarica 54(2):167–178
Bresinsky A, Besl H (1989) A colour atlas of poisonous fungi: a handbook for pharmacists, doctors and biologists. Manson Publ., London, S 168
Laux HE (1985) Eßbare Pilze und ihre giftigen Doppelgänger. Franckh’sche Verlagshandlung, Stuttgart, S 21
Lincoff GH (2000) National Audubon Society Field Guide to Mushrooms. Alfred A. Knopf, New York, S 571
Spiteller P (2013) Chalciporon. In: Römpp – Lexikon der Chemie. https://roempp.thieme.de/roempp4.0/do/data/RD-03-01037
Hartmann-Schreier J, Schweiggert R (2017) Geschmacksschärfe. In: Römpp-Chemie-Lexikon-online. https://roempp.thieme.de/roempp4.0/do/data/RD-07-02401. Zugegriffen: 19. Febr. 2019
Marx W, McKavanagh D, McCarthy AL, Bird R, Ried K, Chan A, Isenring L (2015) The effect of ginger (Zingiber officinale) on platelet aggregation: a systematic literature review. PloS One 10(10):e0141119
Oyagbemi AA, Saba AB, Azeez OI (2010) Molecular targets of [6]-gingerol: Its potential roles in cancer chemoprevention. BioFactors (Oxford, England) 36(3):169–178
Pourmasoumi M, Hadi A, Rafie N, Najafgholizadeh A, Mohammadi H, Rouhani MH (2018) The effect of ginger supplementation on lipid profile: A systematic review and meta-analysis of clinical trials. Phytomedicine: Int J Phytotherapy Phytopharmacol 43:28–36
Proplanta (2018) Ingweranbau in Bayern. https://www.proplanta.de/Agrar-Nachrichten/Pflanze/Ingwer-Anbau-in-Bayern-verzeichnet-erste-Erfolge_article1546090944.html. Zugegriffen: 24. Febr. 2019
Semwal RB, Semwal DK, Combrinck S, Viljoen AM (2015) Gingerols and shogaols: Important nutraceutical principles from ginger. Phytochemistry
Senchina DS, Hallam JE, Kohut ML, Nguyen NA, Perera MADN (2014) Alkaloids and athlete immune function: caffeine, theophylline, gingerol, ephedrine, and their congeners. Exerc Immunol Rev 20
Sicherheitsdatenblatt Sigma-Aldrich (2016) https://www.sigmaaldrich.com/MSDS/MSDS/DisplayMSDSPage.do?country=DE&language=de&brand=SIGMA&productNumber=G1046 Zugegriffen: 20. Febr. 2019
Stanisiere J, Mousset PY, Lafay S (2018) How safe is ginger rhizome for decreasing nausea and vomiting in women during early pregnancy? Foods (Basel, Switzerland) 7(4)
ZDF (2018) Ingweranbau erstmals in Europa. Sendung vom 22.10.2018. https://www.zdf.de/nachrichten/heute-in-europa/ingwer-anbau-erstmals-in-europa-100.html. Zugegriffen: 24. Febr. 2019
Heymann H, Lawless, HT (2013) Sensory evaluation of food: principles and practices. Springer Science & Business Media
Kumar S, Kamboj J, Sharma S (2011) Overview for various aspects of the health benefits of Piper longum Linn. fruit. J Acupunct Meridian Stud 4(2):134–140
Martins AP, Salgueiro L, Vila R, Tomi F, Canigueral S, Casanova, J, Provença da Cunhab A, Adzet T (1998) Essential oils from four Piper species. Phytochem 49(7):2019–2023
Pfennig A, Delinski D, Johannisbauer W, Josten H (2011) Extraction technology-sample extraction of pepper. In: Bart HJ, Pilz St (Hrsg) Industrial scale, natural products extraction. Wiley-VHC, Weinheim, S 191
Römpp (1997) Mauerpfeffer. Falbe J, Regitz M (Hrsg) Römpp Lexikon Chemie. Thieme, Stuttgart, S 2657
Roth L, Daunderer M, Kormann K (2008) Giftpflanzen-Pflanzengifte: Vorkommen, Wirkung, Therapie, allergische und phototoxische Reaktionen; neu: mit Sonderteil über Gifttiere. Nikol, Hamburg, S 649
Literatur: zu Abschn. 4.2.2.2.2
Appendino G, Szallasi A (1997) Euphorbium: modern research on its active principle, resiniferatoxin, revives an ancient medicine. Life Sci 60(10):681–696
Asakawa Y (1995) Sacculatane. In: Herz W, Kirby GW, Moore RE, Steglich W, Tamm CH (Hrsg) Fortschritte der Chemie organischer Naturstoffe 65. Springer, Wien, S 268–272
Asakawa Y (1999) Phytochemistry of bryophytes. In: Phytochemicals in human health protection, nutrition, and plant defense. Springer, Boston, MA, S 319–342
Asakawa Y, Ludwiczuk A, Nagashima F (2013) Biologically active compounds of the marchantiophyta and bryophyta. In: Chemical Constituents of Bryophytes. Springer, Vienna, S 619–638
Brown D (2016) Resiniferatoxin: The evolution of the “molecular scalpel” for chronic pain relief. Pharmaceuticals 9(3):47
Christenhusz MJ, Byng JW (2016) The number of known plants species in the world and its annual increase. Phytotaxa 261(3):201–217
Hausen BM (1997) Frullanoid. In: Hausen BM, Vieluf I (Hrsg.) Allergiepflanzen-Pflanzenallergene. Ecomed, Landsberg a. Lech. S 271
Heiss J, Iadarola M, Cantor F, Oughourli A, Smith R, Mannes A (2014) (364) A Phase I study of the intrathecal administration of resiniferatoxin for treating severe refractory pain associated with advanced cancer. J Pain 15(4):67
Jantwal A, Rana M, Rana AJ, Upadhyay J, Durgapal S (2019) Pharmacological potential of genus marchantia: a review. J Pharmacognosy Phytochem 8(2):641–645
Material safety data sheet (2014) Resiniferatoxin sc 24015. Santa Cruz Biotechnology Inc. http://datasheets.scbt.com/sc-24015.pdf. Zugegriffen: 1. März 2019
Olah Z, Szabo T, Karai L, Hough C, Fields RD, Caudle RM, Blumberg PM, Iadarola MJ (2001) Ligand-induced dynamic membrane changes and cell deletion conferred by vanilloid receptor 1. J Biol Chem 276(14):11021–11030
Raithel SJ, Sapio MR, LaPaglia DM, Iadarola MJ, Mannes AJ (2018) Transcriptional changes in dorsal spinal cord persist after surgical incision despite preemptive analgesia with peripheral resiniferatoxin. Anesthesiology 128(3):620–635. https://doi.org/10.1097/ALN.0000000000002006
Szallasi A, Blumberg PM (1989) Resiniferatoxin, a phorbol-related diterpene, acts as an ultrapotent analog of capsaicin, the irritant constituent in red pepper. Neuroscience 30(2):515–520
Szallasi A, Blumberg PM (1990) Resiniferatoxin and its analogs provide novel insights into the pharmacology of the vanilloid (capsaicin) receptor. Life Sci 47(16):1399–1408
Szallasi A, Blumberg PM (1992) Vanilloid receptor loss in rat sensory ganglia associated with long term desensitization to Resiniferatoxin. Neurosci Lett 140(1):51–54
Literatur zu Abschn. 4.2.2.2.3
Andina D, de Bernardi M, del Vecchio A, Fronza G, Mellerio G, Vidari G, Vita- P (1980) Sesquiterpenes from Russula sardonia. Phytochemistry 19(1):93–97
Anke H, Sterner O (1991) Comparison of the antimicrobial and cytotoxic activities of twenty unsaturated sesquiterpene dialdehydes from plants and mushrooms. Planta Med 57(4):344–346
Bon M (2005) Pareys Buch der Pilze. Franckh-Kosmos, Stuttgart, S 80
Camazine SM, Resch JF, Eisner T, Meinwald J (1983) Mushroom chemical defense. J Chem Ecol 9(10):1439–1447
Forsby A, Andersson M, Lewan L, Sterner O (1991) The cytotoxicity of 22 sesquiterpenoid unsaturated dialdehydes, as determined by the neutral red absorption assay and by protein determination. Toxicol In Vitro 5(1):9–14
List PH, Hackenberg H (1969) Velleral und iso-Velleral, scharf schmeckende Stoffe aus Lactarius vellereus FRIES. Arch Pharm 302(2):125–143
Montag A (1997) Leder für Bekleidung. In: Montag A (Autor) Bedarfsgegenstände: Recht-Technologie-Chemie-Wechselwirkungen. Eine Einführung. Unter Mitwirkung von Andreas Montag. Behr's Verlag, Hamburg. S 228–233
Sterner O, Bergman R, Kihlberg J, Wickberg B (1985) The sesquiterpenes of Lactarius vellereus and their role in a proposed chemical defense system. J Nat Prod 48(2):279–288
Sterner O, Carter RE, Nilsson LM (1987) Structure-activity relationships for unsaturated dialdehydes 1. The mutagenic activity of 18 compounds in the Salmonella/microsome assay. Mutat Res/Genet Toxicol 188(3):169–174
Sterner O (1989) The co-formation of sesquiterpene aldehydes and lactones in injured fruit bodies of Lactarius necator and L. circellatus. The isolation of epi-piperalol. Acta Chem Scand 43:694–697
Literatur zu Abschn. 4.2.3
Covington AD (2009) Tanning chemistry: the science of leather. Royal Society of Chemistry
Cummings AJ (1850) Tannin as a medical agent. Boston Med Surg J (1828–1851) 43(2):36
Geyer J, Herling AW (2016) Pharmakologie der Verdauung. In: Löscher W, Richter A (Hrsg) Lehrbuch der Pharmakologie und Toxikologie in der Veterinärmedizin. Ferdinand Enke, Stuttgart, S 279–323
Haslam E (1966) Chemistry of vegetable tannins. Academic Press London, New York
Khanbabaee K, van Ree T (2001) Tannins: classification and definition. Nat Prod Rep 18(6):641–649
Montag A (1997) Leder für Bekleidung. In: Montag A (Autor) Bedarfsgegenstände: Recht-Technologie-Chemie-Wechselwirkungen. Eine Einführung. Unter Mitwirkung von Andreas Montag. Behr's Verlag, Hamburg. S 228–233
Porter LJ (2012) 11 Tannins. Methods in plant biochemistry 1:389
Reddy MB, Love M (1999) The impact of food processing on the nutritional quality of vitamins and minerals. In Impact of processing on food safety. Springer, Boston, MA, S 99–106
Ruszczyński M, Urbańska M, Szajewska H (2014) Gelatin tannate for treating acute gastroenteritis: a systematic review. Annals of gastroenterology: quarterly publication of the hellenic society of gastroenterology 27(2):121
Steinegger E, Hänsel R (2013) Pharmakognosie. Springer, S 413
Ude M, Hengstler S, Schulz M, Müller WE, Leuner K (2009) Mineralstoffe und Spurenelemente–ein Fall für die Beratung. In der Apotheke. Pharm Unserer Zeit 38(3):268–276
Literatur zu Abschn. 4.2.3.1
Akiyama H, Fujii K, Yamasaki O, Oono T, Iwatsuki K (2001) Antibacterial action of several tannins against Staphylococcus aureus. J Antimicrob Chemother 48(4):487–491
Al‐Ayyoubi S, Gali‐Muhtasib H (2007) Differential apoptosis by gallotannin in human colon cancer cells with distinct p53 status. Molecular Carcinogenesis: Published in cooperation with the University of Texas MD Anderson Cancer Center 46(3):176–186
Baltes W (2000) Zusatzstoffe im Lebensmittelverkehr. In: Lebensmittelchemie. Springer, Berlin, S 154–194
Bedgood DR Jr, Bishop AG, Prenzler PD, Robards K (2005) Analytical approaches to the determination of simple biophenols in forest trees such as Acer (maple), Betula (birch), Coniferus, Eucalyptus, Juniperus (cedar), Picea (spruce) and Quercus (oak). Analyst 130(6):809–823
Bhandary BSK, Sharmila KP, Kumari NS, Bhat SV (2013) Acute and subacute toxicity study of the ethanol extracts of Punica granatum (Linn). Whole fruit and seeds and synthetic ellagic acid in swiss albino mice. Asian J Pharm Clin Res 6(4):192–198
Bulani VD, Kothavade PS, Nagmoti DM, Kundaikar HS, Degani MS, Juvekar AR (2015) Characterisation and anti-inflammatory evaluation of the inclusion complex of ellagic acid with hydroxypropyl-β-cyclodextrin. J Incl Phenom Macrocycl Chem 82(3–4):361–372
Fink M (2002) Einsatz der Nah-Infrarot (NIR)-Spektroskopie zur quantitativen Bestimmung ausgewählter pflanzlicher Inhaltsstoffe. Von der gemeinsamen Naturwissenschaftlichen Fakultät der Technischen Universität Carolo-Wilhelmina zu Brauschweig zur Erlangung des Grades einer Doktorin der Naturwissenschaften genehmigte Dissertation. https://d-nb.info/968061184/34. Zugegriffen: 10. März 2019
Fukuda T, Ito H, Yoshida T (2003) Antioxidative polyphenols from walnuts (Juglans regia L.). Phytochemistry 63(7):795–801
Daniel EM, Krupnick AS, Heur YH, Blinzler JA, Nims RW, Stoner GD (1989) Extraction, stability, and quantitation of ellagic acid in various fruits and nuts. J Food Compos Anal 2(4):338–349
Gómez- AM, Verardo V, Toselli M, Segura- A, Fernández-Gutiérrez A, Caboni MF (2013) Determination of the major phenolic compounds in pomegranate juices by HPLC–DAD–ESI-MS. J Agric Food Chem 61(22):5328–5337
Gudej J, Tomczyk M (2004) Determination of flavonoids, tannins and ellagic acid in leaves from Rubus L. species. Arch Pharmacal Res 27(11):1114–1119
Hagerman AE (2002) Hydrolyzable tannin structural chemistry. Tannin handbook, 1–5
Haslam E (1992) Gallic acid and its metabolites. In: Hemingway RW, Laks PE (Hrsg) Plant Polyphenols: Synthesis, Properties, Significance, S 169–193
Laslo E, Köbölkuti ZA (2017) Total phenol content and antimicrobial activity of lingonberry (Vaccinium vitis-idaea L.) from several areas in the eastern Carpathians. Notulae Sci Biologicae 9(1):77–83
Löwe J (1868) Über die Bildung von Ellagsäure aus Gallussäure. Z Chem 4:603
Mertens-Talcott SU, Percival SS (2005) Ellagic acid and quercetin interact synergistically with resveratrol in the induction of apoptosis and cause transient cell cycle arrest in human leukemia cells. Cancer Lett 218(2):141–152
Montag A, Reinel D (1997) Teer-Präparate in der Dermatologie. Dermatosen in Beruf und Umwelt 45(1):22–24
Morimoto S, Nonaka GI, Nishioka I (1987) Tannins and Related Compounds. LIX. Aesculitannins, Novel Proanthocyanidins with Doubly-Bonded Structures from Aesculus hippocastanum L. Chem Pharm Bull 35(12):4717–4729
Ortega A, Domingo JL, Gómez M, Corbella J (1989) Treatment of experimental acute uranium poisoning by chelating agents. Pharmacol Toxicol 64(3):247–251
Ozawa T, Kobayashi S, Seki R, Imagawa H (1984) A new gallotannin from bark of chestnut tree, Castanea crenata sieb. et zucc. Agric Bio Chem 48(6):1411–1416
Ring J, Fröhlich HH (1985) Antiphlogistika (ausgenommen Glukokortikosteroide) und Venenmittel. In: Wirkstoffe in der dermatologischen Therapie. Springer, Berlin, S 184–193
Römpp (2002) Gallussäure. In: Dill B, Heiker FR, Kirsching A (Hrsg) Römpp Lexikon Chemie-online. https://roempp.thieme.de/roempp4.0/do/data/RD-07-00113. Zugegriffen: 5. März 2019
Rul EF, Khaikin MS, Fedorina LG, Derstuganoff EF (1967) The tanning-developing properties of some polyoxy con1pounds. J Photographic Sci 15(4):174–180
Scalbert A (1991) Antimicrobial properties of tannins. Phytochemistry 30(12):3875–3883
Schlesier K (2002) Untersuchungen zum Polyphenolspektrum und zur antioxidativen Wirkung von Tee und Wechselwirkungen von Teepolyphenolen mit Eisen. Dissertation zur Erlangung des akademischen Grades doctor rerum naturalium. Vorgelegt dem Rat der biologisch-pharmazeutischen Fakultät der Friedrich-Schiller-Universität Jena. http://www.bioaktive-pflanzenstoffe.uni-jena.de/docs/Dissertation_Karin_Schlesier_2002.pdf. Zugegriffen: 10. März 2019
Seeram NP, Lee R, Scheuller HS, Heber D (2006) Identification of phenolic compounds in strawberries by liquid chromatography electrospray ionization mass spectroscopy. Food Chem 97(1):1–11
Sticher O (2010) Phenolische Verbindungen. In: Hänsel R, Sticher O (Hrsg) Pharmakognosie—Phytopharmazie. Springer, Berlin, S 1051–1215
Stoner GD, Mukhtar H (1995) Polyphenols as cancer chemopreventive agents. J Cell Biochem 22:169–180
Takos AM, Ubi BE, Robinson SP, Walker AR (2006) Condensed tannin biosynthesis genes are regulated separately from other flavonoid biosynthesis genes in apple fruit skin. Plant Sci 170(3):487–499
Yamanaka D, Motoi M, Ishibashi KI, Miura NN, Adachi Y, Ohno N (2013) Modulation of interferon-γ synthesis by the effects of lignin-like enzymatically polymerized polyphenols on antigen-presenting cell activation and the subsequent cell-to-cell interactions. Food Chem 141(4):4073–4080
Zahn T, Hensel A (2017) Birkenrindenextrakt zur Wundheilung. Deutsche Apotheker Zeitung (47) 34. https://www.deutsche-apotheker-zeitung.de/daz-az/2017/daz-47-2017/birkenrindenextrakt-zur-wundheilung. Zugegriffen: 24. Mai 2020
Zekert O (1936) Carl Wilhelm Scheele. Gedenkschrift zum 150. Todestage. Springer, Berlin, S 1–57
Zhao T, Sun Q, del Rincon SV, Lovato A, Marques M, Witcher M (2014) Gallotannin imposes S phase arrest in breast cancer cells and suppresses the growth of triple-negative tumors in vivo. PloS one 9(3):e92853
Literatur zu Abschn. 4.2.3.2
Afoakwa EO, Quao J, Takrama J, Budu AS, Saalia FK (2012) Changes in total polyphenols, O-diphenols and anthocyanin concentrations during fermentation of pulp pre-conditioned cocoa (Theobroma cacao) beans. Int Food Res J 19(3):1071–1077
Aizpurua-Olaizola O, Ormazabal M, Vallejo A, Olivares M, Navarro P, Etxebarria N, Usobiaga A (2015) Optimization of supercritical fluid consecutive extractions of fatty acids and polyphenols from Vitis vinifera grape wastes. J Food Sci 80(1):101–107
Actis-Goretta L, Lévèques A, Rein M, Teml A, Schäfer C, Hofmann U, Li H, Schwab M, Eichelbaum M, Williamson G (2013) Intestinal absorption, metabolism and excretion of (−)-epicatechin in healthy humans assessed by using an intestinal perfusion technique. Am J Clin Nutr 98(4):924–933
Bayard V, Chamorro F, Motta J, Hollenberg NK (2007) Does flavanol intake influence mortality from nitric oxide-dependent processes? Ischemic heart disease, stroke, diabetes mellitus, and cancer in Panama. Int J Med Sci 4(1):53
Belz GG, Mohr- S (2011) Kakao und dunkle Schokolade zur kardiovaskulären Prävention? DMW-Dtsch Med Wochenschr 136(51/52):2657–2663
Bhagwat S, Haytowitz DB, Holden JM (2014) USDA database for the flavonoid content of selected foods, Release 3.1. US Department of Agriculture: Beltsville, MD, USA
Chen ZP, Schell JB, Ho CT, Chen KY (1998) Green tea epigallocatechin gallate shows a pronounced growth inhibitory effect on cancerous cells but not on their normal counterparts. Cancer Lett 129(2):173–179
Clouth A, Schöfer H (2015) Treatment of recalcitrant facial verrucae vulgares with sinecatechins (greentea catechins) ointment. J Eur Acad Dermatol Venereol 29(1):178–179
Chun OK, Chung SJ, Song WO (2007) Estimated dietary flavonoid intake and major food sources of US adults. J Nutr 137(5):1244–1252
Dönmez Ö, Mogol BA, Gökmen V, Tang N, Andersen ML, Chatterton DE (2020) Modulation of gastrointestinal digestion of β-lactoglobulin and micellar casein following binding by (−)-epigallocatechin-3-gallate (EGCG) and green tea flavanols. Food & function, 11(7), 6038-6053
Dräger B, Stintzing FC (2011) Proanthocyanidine. In: Dill B, Böckler F, Kirschning A (Hrsg.) Römpp-online. Lexikon Chemie. https://roempp.thieme.de/roempp4.0/do/data/RD-16-04136. Zugegriffen: 10. März 2019
EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS) (2018) Younes M, Aggett P, Aguilar F, Crebelli R, Dusemund B, Filipic M, Frutos MJ, Galtier P, Gott D, Gundert-Remy U, Lambré, Leblanc JC, Moldeus P, Mortensen A, Oskarsson A, Stankovic I, Waalkens-Berendsen IW, Woutersen RA, Andrade RJ, Fortes C, Mosesso P, Restani P, Arcella D, Pizzo F, Smeraldi C, Wright M (2018) Scientific opinion on the safety of green tea catechins. https://doi.org/10.2903/j.efsa.2018.5239. Zugegriffen: 13. März 2019
Ferreira D (1999) Vol. 3. Carbohydrates and their derivatives including tannins, cellulose and related lignins. In: Barton S, Nakanishi K, Meth-Cohn O (Hrsg) Comprehensive natural products chemistry, Bd 1–9, Elsevier, Oxford, S 747
Freudenberg K, Cox RF, Braun E (1932) The Catechin of the Cacao Bean 1. J Am Chem Soc 54(5):1913–1917
Hara Y (2001) Green tea – health benefits and applications. Taylor & Francis, London
Hooper L, Kay C, Abdelhamid A, Kroon PA, Cohn JS, Rimm EB, Cassidy A (2012) Effects of chocolate, cocoa, and flavan-3-ols on cardiovascular health: a systematic review and meta-analysis of randomized trials. Am J Clin Nutr 95(3):740–751
Hu J, Webster D, Cao J, Shao A (2018) The safety of green tea and green tea extracts consumption in adults–results of a systematic review. Regul Toxicol Pharmacol 95:412–433
Jones C, Woods K, Whittle G, Worthington H, Taylor G (1999) Sugar, drinks, deprivation and dental caries in 14-year-old children in the north west of England in 1995. Commun Dent Health 16(2):68–71
Khalesi S, Sun J, Buys N, Jamshidi A, Nikbakht-Nasrabadi E, Khosravi-Boroujeni H (2014) Green tea catechins and blood pressure: a systematic review and meta-analysis of randomised controlled trials. Eur J Nutr 53(6):1299–1311
Julkunen-Tiitto R, Sorsa S (2001) Testing the effects of drying methods on willow flavonoids, tannins, and salicylates. J Chem Ecol 27(4):779–789
Liu H, Zou T, Gao JM, Gu L (2013) Depolymerization of cranberry procyanidins using (+)-catechin,(−)-epicatechin, and (−)-epigallocatechin gallate as chain breakers. Food Chem 141(1):488–494
Lorenz M, Urban J, Engelhardt U, Baumann G, Stangl K, Stangl V (2009) Green and black tea are equally potent stimuli of NO production and vasodilation: new insights into tea ingredients involved. Basic Res Cardiol 104(1):100–110
Määttä-Riihinen KR, Kähkönen MP, Törrönen AR, Heinonen IM (2005) Catechins and procyanidins in berries of Vaccinium species and their antioxidant activity. J Agric Food Chem 53(22):8485–8491
Martinez SE, Davies NM, Reynolds JK (2013) Toxicology and safety of flavonoids. Flavonoid Pharmacokinetics: Methods of Analysis, Preclinical and Clinical Pharmacokinetics, Safety, and Toxicology, 249–280.
Meloni G, Milani M (2018) Efficacy and tolerability of topical green tea extract (polyphenon E) Application in a “Therapy-Resistant” Plantar Wart. Case Rep Dermatol 10(2):127–132
Morimoto S, Nonaka GI, Nishioka I (1987) Tannins and Related Compounds. LIX. Aesculitannins, Novel Proanthocyanidins with Doubly-Bonded Structures from Aesculus hippocastanum L. Chem Pharm Bull 35(12):4717–4729
NCBI (National Center for Biotechnology Information) (2019) (−)-Epigallocatechin gallate. PubChem Compound Database; CID=65064, https://pubchem.ncbi.nlm.nih.gov/compound/65064. Zugegriffen: 10. März 2019
Orians CM, Fritz RS (1995) Secondary chemistry of hybrid and parental willows: Phenolic glycosides and condensed tannins in Salix sericea, S. eriocephala, and their hybrids. J Chem Ecol 21(9):1245–1253
Ottaviani JI, Momma TY, Kuhnle GK, Keen CL, Schroeter H (2012) Structurally related (−)-epicatechin metabolites in humans: Assessment using de novo chemically synthesized authentic standards. Free Radical Biol Med 52(8):1403–1412
Otteneder H, Schreier P (2012) Catechine. In: Dill B, Böckler F, Kirschning A (Hrsg) Römpp-online. Lexikon Chemie. https://roempp.thieme.de/roempp4.0/do/data/RD-03-00674. Zugegriffen: 10. März 2019
Pelzer FJ (1837) Vollständiges Handbuch der gesammten Lederfabrikation theoretisch und praktisch bearbeitet: nebst einer neuen nach chemisch technischen Grundsätzen aufgestellten und praktisch erprobten Schnellgerberei, mit Einschluß aller bis jetzt bekannt gewordenen Gerbearten. Bädeker, Leipzig
Pietta PG (2000) Flavonoids as antioxidants. J Nat Prod 63(7):1035–1042
Primetta A (2018) Phenolic compounds in the berries of the selected vaccinium species the potential for authenticity analyses. Academic Dissertation of Forestry and Natural Sciences.
Kuopio, 2014 Пocтyпилo в peдaкцию 14 нoябpя 1, 7–37. https://www.researchgate.net/publication/272172300_Phenolic_compounds_in_the_berries_of_the_selected_Vaccinium_species_The_potential_for_authenticity_analyses. Zugegriffen: 20. April 2019
Ried K, Sullivan TR, Fakler P, Frank OR, Stocks NP (2012) Effect of cocoa on blood pressure. Cochrane Database of Systematic Reviews (8)
Schlesier K (2002) Untersuchungen zum Polyphenolspektrum und zur antioxidativen Wirkung von Tee und Wechselwirkungen von Teepolyphenolen mit Eisen. Dissertation zur Erlangung des akademischen Grades doctor rerum naturalium. Vorgelegt dem Rat der biologisch-pharmazeutischen Fakultät der Friedrich-Schiller-Universität Jena. http://www.bioaktive-pflanzenstoffe.uni-jena.de/docs/Dissertation_Karin_Schlesier_2002.pdf. Zugegriffen: 10. März 2019
Stacewicz-Sapuntzakis M, Bowen PE, Hussain EA, Damayanti-Wood BI, Farnsworth NR (2001) Chemical composition and potential health effects of prunes: a functional food? Crit Rev Food Sci Nutr 41(4):251–286
Tatti S, Swinehart JM, Thielert C, Tawfik H, Mescheder A, Beutner KR (2008) Sinecatechins, a defined green tea extract, in the treatment of external anogenital warts: a randomized controlled trial. Obstet Gynecol 111(6):1371–1379
Türk O (2014) Tannine. In: Stoffliche Nutzung nachwachsender Rohstoffe. Grundlagen-Werkstoffe-Anwendungen. Springer, Wiesbaden, S 471
Vogiatzoglou A, Mulligan AA, Lentjes MA, Luben RN, Spencer JP, Schroeter H, Khaw KT, Kuhnle GGC, (2015) Flavonoid intake in European adults (18 to 64 years). PloS one 10(5):e0128132
von Lippmann EO (1921) Zeittafeln zur Geschichte der organischen Chemie. In Zeittafeln zur Geschichte der Organischen Chemie. Springer, Berlin, S 1–56
Wollgast J, Anklam E (2000) Polyphenols in Theobroma cacao: Changes in composition during the manufacture of chocolate and methodology for identification and quantification: A review. Food Res Int 33(2000):423–447
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Montag, A. (2023). Toxische Abwehrstrategien der Pflanzen in Europa. In: Pflanzen und Haut . Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-63014-3_4
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