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Molecular Basis and Genetic Regulation of EPS

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Microbial Exopolysaccharides as Novel and Significant Biomaterials

Part of the book series: Springer Series on Polymer and Composite Materials ((SSPCM))

Abstract

The diverse world of exopolysaccharides (EPS) is contributed by bacteria, archaea, fungi, micro, and macroalgae. EPS are biosynthesized via Wzx/Wzy-dependent pathway, ABC transporter-dependent pathway, or synthase-dependent pathway, that connect to sugar and amino acid metabolism pathways. Relatively conserved gene clusters and regulons govern the EPS biosynthesis. Branching and functional group decorations introduce structural and functional diversities. Exceptional EPS synthesized by the extremophiles indicate the modifications in these operons. Since EPS production is a strategy for protection in hostile environments, several transcriptional and translational regulatory networks control its synthesis. Even though whole-genome analysis of some EPS-producing bacteria has annotated the essential genes and regulators of EPS biosynthesis, there is a lot to uncover concerning cyanobacteria and eukaryotic producers. These steps will work toward the manufacture of tailored EPS variants with the potential to be used as valuable renewable and high-performance products for industrial applications.

Genes are like the story and DNA is the language that the story is written in.

Sam Kean.

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Acknowledgements

SK thanks UGC for providing her Senior Research Fellowship. SK is also thankful to Prof. C. Jayabaskaran, Department of Biochemistry, Indian Institute of Science, for his constant encouragement and support.

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  1. Department of Biochemistry, Indian Institute of Science, Bengaluru, India

    Siya Kamat

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  1. Department of Biotechnology and Bioinformatics, Jaypee University of Information Technology, Waknaghat, Himachal Pradesh, India

    Ashok Kumar Nadda

  2. Department of Biochemistry, Indian Institute of Science, Bengaluru, Karnataka, India

    Sajna K. V.

  3. University Institute of Biotechnology (UIBT), Chandigarh University, Mohali, Punjab, India

    Swati Sharma

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Kamat, S. (2021). Molecular Basis and Genetic Regulation of EPS. In: Nadda, A.K., K. V., S., Sharma, S. (eds) Microbial Exopolysaccharides as Novel and Significant Biomaterials. Springer Series on Polymer and Composite Materials. Springer, Cham. https://doi.org/10.1007/978-3-030-75289-7_3

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